Amiloride Hydrochloride Dihydrate: A Comprehensive Guide
Understanding the properties, applications, and market of this vital pharmaceutical ingredient.
Get a Quote & SampleProduct Core Value

Amiloride Hydrochloride Dihydrate
Amiloride Hydrochloride Dihydrate is a crucial pyrazine derivative known for its potent antikaliuretic and diuretic properties. It acts as an epithelial sodium channel blocker, playing a vital role in managing hypertension and congestive heart failure by regulating sodium and water balance in the body, while importantly sparing potassium loss.
- Amiloride hydrochloride mechanism of action involves inhibiting sodium reabsorption in the kidneys, thereby influencing fluid balance and blood pressure.
- The Amiloride hydrochloride properties include its effectiveness as a potassium-sparing agent, making it a valuable adjunctive therapy.
- This compound is essential for the Amiloride hydrochloride for hypertension treatment protocols and managing symptoms associated with congestive heart failure.
- As a key Amiloride hydrochloride API, its quality and availability are critical for pharmaceutical manufacturing processes.
Key Advantages
Potassium Sparing Diuresis
The primary advantage of Amiloride Hydrochloride Dihydrate is its ability to promote sodium and water excretion without causing excessive potassium depletion, a common issue with other diuretics. This characteristic is vital for patients at risk of hypokalemia.
Cardiovascular Support
Its role in managing hypertension and congestive heart failure underscores its importance in cardiovascular health. By reducing fluid overload and blood pressure, it significantly improves patient outcomes.
Therapeutic Versatility
Often used in combination therapy with other diuretics, Amiloride Hydrochloride Dihydrate offers a versatile approach to managing complex fluid and electrolyte imbalances, enhancing overall treatment efficacy.
Key Applications
Hypertension Management
Effectively lowers blood pressure by facilitating sodium and water excretion, contributing to better cardiovascular health for patients suffering from high blood pressure.
Congestive Heart Failure Treatment
Helps reduce fluid buildup and edema associated with congestive heart failure, improving cardiac function and patient comfort.
Adjunctive Diuretic Therapy
Works synergistically with other diuretics to provide comprehensive treatment for conditions requiring careful fluid and electrolyte balance.
Pharmaceutical Ingredient
Serves as a critical Active Pharmaceutical Ingredient (API) for the formulation of medications aimed at treating cardiovascular and renal conditions.