NINGBO INNO PHARMCHEM CO.,LTD. is a leading supplier of high-quality chemical compounds, including vital pharmaceutical ingredients like Sulfamethazine. With a molecular formula of C12H14N4O2S and CAS number 57-68-1, Sulfamethazine is a synthetic antimicrobial agent belonging to the sulfonamide class. Its pharmacological profile, from its chemical structure to its diverse applications, is crucial for understanding its significance in veterinary medicine.

The synthesis of Sulfamethazine, like other sulfonamides, involves complex chemical processes to achieve its specific molecular structure. This structure allows it to act as an antimetabolite, specifically by mimicking para-aminobenzoic acid (PABA), a substance essential for bacterial folic acid synthesis. The sulfamethazine mechanism of action is centered on blocking the enzyme dihydropteroate synthase, thereby inhibiting the production of dihydrofolic acid. This disruption prevents bacteria from synthesizing purines and thymidine, ultimately halting their growth and replication. This precise mechanism underpins the sulfamethazine antibacterial spectrum, which covers a wide range of Gram-positive and Gram-negative bacteria, as well as certain protozoa.

In terms of physical properties, Sulfamethazine typically appears as a white or almost white powder, with a characteristic melting point around 197°C, often accompanied by decomposition. These properties are important for formulation and stability. The packaging and storage of Sulfamethazine are also critical; it is usually supplied in drums, requiring storage in a cool, dry, and ventilated environment away from direct sunlight and incompatible materials.

The applications of Sulfamethazine in veterinary medicine are extensive. It is widely used to treat and prevent bacterial infections in a variety of animal species, including poultry, cattle, and swine. Conditions such as avian cholera, avian typhoid, coccidiosis, and various respiratory and urinary tract infections fall within its therapeutic scope. The understanding of sulfadimidine sodium applications further broadens its utility, particularly in formulations requiring enhanced solubility.

It is also important for users to be aware of potential sulfamethazine adverse effects in animals and to follow recommended dosage guidelines to ensure safety and efficacy. NINGBO INNO PHARMCHEM CO.,LTD. provides reliable, high-purity Sulfamethazine, supporting the critical work of veterinarians and researchers in maintaining animal health and advancing pharmaceutical science.