Understanding the Chemical Properties of 4-Fluorobenzoyl Chloride (CAS 403-43-0)
To fully leverage the capabilities of chemical intermediates, understanding their fundamental properties is key. NINGBO INNO PHARMCHEM CO.,LTD. offers insight into the chemical and physical characteristics of 4-Fluorobenzoyl Chloride (CAS 403-43-0), a compound vital for numerous synthetic processes.
4-Fluorobenzoyl Chloride is characterized by its appearance as a colorless liquid, a common trait for acyl chlorides. Its molecular formula is C7H4ClFO, and it has a molecular weight of approximately 158.56 g/mol. Key physical properties include a melting point typically around 10-12 °C and a boiling point of approximately 82 °C at 20 mmHg. The density is reported to be around 1.342 g/mL at 25 °C, indicating it is denser than water. These specifications are critical for handling, storage, and reaction design.
Chemically, 4-Fluorobenzoyl Chloride is highly reactive, primarily due to the acyl chloride functional group. This makes it an excellent acylating agent, readily participating in reactions with nucleophiles such as alcohols, amines, and water to form esters, amides, and carboxylic acids, respectively. The presence of the fluorine atom on the aromatic ring influences the electron distribution and reactivity, often leading to enhanced stability and altered biological activity in the resultant compounds.
The compound's utility spans across various sectors. In the pharmaceutical industry, it serves as a building block for synthesizing drugs where the fluorobenzoyl moiety is critical for efficacy. For pesticide manufacturing, it aids in creating active ingredients with targeted action. In dye synthesis, it can contribute to the development of colors with unique spectral properties and improved fastness. For businesses looking to buy 4-Fluorobenzoyl Chloride, understanding these properties ensures its correct application.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying 4-Fluorobenzoyl Chloride that meets stringent quality standards, including high purity levels (≥99%). This dedication ensures that researchers and manufacturers can rely on its predictable reactivity and performance. Our expertise in organic synthesis intermediates means we are well-equipped to meet the diverse needs of our clients who utilize this versatile compound.
Perspectives & Insights
Agile Reader One
“Chemically, 4-Fluorobenzoyl Chloride is highly reactive, primarily due to the acyl chloride functional group.”
Logic Vision Labs
“This makes it an excellent acylating agent, readily participating in reactions with nucleophiles such as alcohols, amines, and water to form esters, amides, and carboxylic acids, respectively.”
Molecule Origin 88
“The presence of the fluorine atom on the aromatic ring influences the electron distribution and reactivity, often leading to enhanced stability and altered biological activity in the resultant compounds.”