NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of supplying essential chemical compounds, and 8-hydroxyquinoline sulfate (CAS: 134-31-6) is one such critical intermediate. This yellow crystalline powder, identified by its molecular formula C18H16N2O6S, is a salt of 8-hydroxyquinoline. Its chemical structure and reactivity lend it to a variety of important applications, from being a building block in pharmaceuticals and dyes to its use in analytical chemistry.

Delving into the 8-hydroxyquinoline sulfate chemical properties reveals its nature as a heterocyclic compound. It exhibits antimicrobial and chelating activities. The latter property is particularly significant; it forms complexes with various metal ions, making it useful for metal ion extraction and as a complexometric titration indicator. Standard specifications for high-quality 8-hydroxyquinoline sulfate include a purity of ≥99.0%, with tight controls on residue on ignition (≤0.2%) and loss on drying (≤0.2%). The melting point, typically between 175-178°C, is another key indicator of its purity and quality.

The synthesis of 8-hydroxyquinoline itself, from which the sulfate salt is derived, involves several chemical steps. While specific proprietary methods may vary, general approaches often involve the cyclization of aromatic precursors. For instance, a method might include reacting o-aminophenol or o-nitrophenol with concentrated sulfuric acid under controlled heating conditions, often in the presence of catalysts like copper sulfate. The subsequent isolation and purification steps are critical to achieving the high purity required for its applications. Understanding these processes helps in appreciating the value provided by a reliable 8-hydroxyquinoline sulfate supplier like NINGBO INNO PHARMCHEM CO.,LTD.

The analytical significance of 8-hydroxyquinoline sulfate lies in its ability to detect and quantify metal ions. Its complex formation with metals allows for gravimetric analysis, spectrophotometric determination, and as mentioned, complexometric titrations. This makes it an invaluable reagent in laboratories for quality control, environmental testing, and research. For those needing to buy 8-hydroxyquinoline sulfate for analytical purposes, ensuring high assay and low impurity levels is paramount.

As a chemical intermediate, 8-hydroxyquinoline sulfate is foundational for many organic syntheses. Its role in creating halogenated quinoline drugs, for example, highlights its importance in pharmaceutical chemistry. The consistent quality and availability from NINGBO INNO PHARMCHEM CO.,LTD. support the steady supply chain for these essential medications. Furthermore, discussions around 8-hydroxyquinoline sulfate safety are ongoing, with regulatory bodies setting usage limits in consumer products to ensure public health. Manufacturers must be aware of these guidelines when utilizing the compound.

In conclusion, 8-hydroxyquinoline sulfate is a chemically significant compound with a wide range of applications driven by its unique properties. Its synthesis and purification are critical to its utility, and its role as an analytical reagent and chemical intermediate is well-established. NINGBO INNO PHARMCHEM CO.,LTD. provides this high-quality compound, supporting advancements in chemistry, pharmaceuticals, and beyond.