Understanding the Synthesis and Properties of 3-Chlorobenzaldehyde
At NINGBO INNO PHARMCHEM CO.,LTD., we believe in empowering our clients with comprehensive knowledge about the chemicals they utilize. This article focuses on 3-Chlorobenzaldehyde (CAS: 587-04-2), detailing its synthesis pathways and fundamental chemical properties, which are crucial for its effective application in various industries.
The synthesis of 3-Chlorobenzaldehyde can be achieved through several established organic chemistry methods. Common routes involve the oxidation of 3-chlorotoluene derivatives or the formylation of chlorobenzene. For instance, one prevalent method utilizes the Vilsmeier-Haack reaction or Gattermann-Koch reaction on chlorobenzene under specific catalytic conditions. The choice of synthesis route often depends on factors such as desired purity, yield, cost-effectiveness, and available starting materials. NINGBO INNO PHARMCHEM CO.,LTD. focuses on optimized production processes to ensure a high-quality and reliable supply of 3-chlorobenzaldehyde.
Chemically, 3-Chlorobenzaldehyde is an aromatic aldehyde, with the molecular formula C7H5ClO and a molecular weight of approximately 140.57 g/mol. Its physical appearance is typically a clear, colorless to light yellow liquid. The melting point is low, usually between 9-12 °C, and it has a boiling point around 213-214 °C. Its density is approximately 1.241 g/mL at 25 °C. A key characteristic of 3-chlorobenzaldehyde is its solubility profile: it is readily soluble in common organic solvents such as ethanol, ether, and acetone, but exhibits low solubility in water due to its hydrophobic aromatic nature.
The reactivity of 3-Chlorobenzaldehyde is defined by both the aldehyde functional group and the presence of the chlorine atom on the benzene ring. The aldehyde group can undergo typical reactions like oxidation to form 3-chlorobenzoic acid, reduction to 3-chlorobenzyl alcohol, and various condensation reactions with amines or active methylene compounds. The chlorine atom, positioned in the meta position, influences the electron density of the aromatic ring and can also be a site for nucleophilic substitution under specific, often harsh, conditions.
Understanding these synthesis methods and properties is essential for anyone looking to buy 3-chlorobenzaldehyde. Whether for pharmaceutical intermediate applications, dye synthesis, or specialty chemicals, the consistent quality and well-defined characteristics of 3-Chlorobenzaldehyde from NINGBO INNO PHARMCHEM CO.,LTD. ensure successful integration into complex chemical processes. Our commitment to providing detailed product information and high-purity materials makes us a preferred 3-chlorobenzaldehyde supplier.
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“This article focuses on 3-Chlorobenzaldehyde (CAS: 587-04-2), detailing its synthesis pathways and fundamental chemical properties, which are crucial for its effective application in various industries.”
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“The synthesis of 3-Chlorobenzaldehyde can be achieved through several established organic chemistry methods.”