In the vast landscape of specialty chemicals, 4-Hydroxy-TEMPO (CAS 2226-96-2) stands out as a compound with significant industrial and research relevance. This stable nitroxyl radical possesses a unique combination of properties that make it invaluable across several sectors. Understanding its science, synthesis, and market position is crucial for anyone involved in advanced chemical applications.

Chemical Identity and Properties

4-Hydroxy-TEMPO, formally known as 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl, is characterized by its stable free radical. Its molecular formula is C9H18NO2, with a molecular weight of approximately 172.25 g/mol. It typically appears as an orange-red powder or crystals. Key properties include its solubility in water and various polar organic solvents, making it amenable to diverse reaction conditions and formulations. Its stability as a radical, due to steric hindrance from the methyl groups and delocalization of the unpaired electron, is fundamental to its functionality.

Synthesis Pathways and Industrial Production

The industrial synthesis of 4-Hydroxy-TEMPO generally involves the oxidation of 2,2,6,6-tetramethyl-4-piperidinol. The precursor itself is often derived from readily available starting materials like acetone and ammonia. The commercial availability of 4-Hydroxy-TEMPO from manufacturers such as NINGBO INNO PHARMCHEM CO.,LTD. ensures a stable supply for its various applications. The production scale is geared towards meeting the demands for its use as a polymerization inhibitor and as an intermediate for other high-value chemicals.

Key Industrial Applications

The market demand for 4-Hydroxy-TEMPO is driven by its critical roles in industry:

  • Polymerization Inhibition: It is a highly effective inhibitor for olefin monomers like styrene, acrylates, and methacrylates, preventing premature polymerization during storage and transport.
  • HALS Synthesis: It serves as a vital intermediate in the production of Hindered Amine Light Stabilizers (HALS), which are essential for protecting polymers and coatings from UV degradation.
  • Antioxidant and Research: Its radical scavenging and antioxidant properties are utilized in biochemical research, and it is explored for potential pharmaceutical applications.

Market Outlook and Sourcing

The demand for 4-Hydroxy-TEMPO is closely tied to the growth of the plastics, coatings, and specialty chemicals industries. As these sectors continue to expand, driven by demand for durable, long-lasting materials, the market for effective stabilizers and intermediates like 4-Hydroxy-TEMPO is expected to remain strong. Sourcing this chemical from reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is crucial for maintaining supply chain stability and product quality.

Understanding the science behind 4-Hydroxy-TEMPO empowers businesses to leverage its full potential, from ensuring product stability to developing next-generation materials. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality 4-Hydroxy-TEMPO to meet the evolving needs of the chemical industry.