At NINGBO INNO PHARMCHEM CO.,LTD., we understand that the success of a formulation often hinges on the precise selection of excipients. Microcrystalline Cellulose (MCC) is a prime example, available in various grades, each offering distinct advantages for specific applications, particularly in pharmaceutical tablet manufacturing.

The different grades of MCC, often identified by numbers like 101, 102, 200, 301, and 302, primarily vary in their particle size, bulk density, and moisture content. These variations directly influence their performance characteristics, such as flowability, compressibility, and binding strength.

For instance, MCC 101, known for its fine particle size, is highly suitable for wet granulation processes and exhibits excellent direct compression properties. MCC 102, with a slightly larger average particle size and high compressibility, is one of the most commonly used grades, balancing performance and ease of handling. Understanding the benefits of using microcrystalline cellulose pharmaceutical grade is crucial for process optimization.

Grades like MCC 200, featuring larger particles, offer superior flowing properties, making them ideal for correcting API flow deficiencies in formulations. MCC 301 and 302 are similar to 101 and 102 respectively but possess a larger bulk density, which can influence tablet weight uniformity and handling characteristics.

Selecting the appropriate MCC grade is essential for achieving desired tablet attributes like hardness, disintegration time, and dissolution rate. For example, a finer particle size might enhance binding, while a lower moisture content could be critical for moisture-sensitive APIs. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing a range of high-quality MCC products and the technical expertise to help you choose the perfect grade for your needs, ensuring optimal results for your pharmaceutical formulations.