2-Ketoglutaric acid, also known as alpha-ketoglutaric acid (AKG) with CAS number 328-50-7, is a compound of significant interest across various industries, primarily due to its high purity and versatile chemical properties. This white crystalline powder serves as a vital intermediate in both biological and industrial processes, making its precise specifications a critical factor for end-users.

The chemical structure of 2-ketoglutaric acid lends itself to a primary role within the Krebs cycle, where it acts as a key intermediate in energy metabolism. However, its industrial applications extend far beyond this biological function. As a food additive, it can contribute to flavor enhancement and nutritional fortification, requiring stringent purity standards to meet food safety regulations.

In the pharmaceutical sector, 2-ketoglutaric acid serves as a crucial building block or intermediate in the synthesis of various active pharmaceutical ingredients (APIs) and complex organic molecules. The efficacy and safety of the final pharmaceutical product are directly influenced by the purity of the starting materials. Therefore, sourcing high-purity 2-ketoglutaric acid is non-negotiable for manufacturers in this field.

When you buy 2-ketoglutaric acid, understanding its specifications, such as assay percentage (often exceeding 99%), loss on drying, and residue on ignition, is paramount. These metrics ensure that the product performs as expected in its intended application, whether it's for precise chemical reactions in pharmaceuticals or for safe consumption as a food additive.

The accessibility of 2-ketoglutaric acid powder through online channels has democratized access for researchers and manufacturers. However, it is important to partner with reliable suppliers who provide comprehensive product documentation, including Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS), to verify purity and handling guidelines.

The price of 2-ketoglutaric acid can vary based on purity, quantity, and supplier. However, the investment in a high-quality, pure product is often justified by the improved outcomes in manufacturing processes and the reduced risk of downstream product contamination or failure.

In essence, the widespread use of 2-ketoglutaric acid in the food and pharmaceutical industries underscores the importance of its purity. As a foundational chemical intermediate, its reliable supply and consistent quality are key to innovation and product development across these critical sectors.