At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing in-depth knowledge about the chemical ingredients that shape our world, particularly within the fragrance and flavor industries. This article focuses on Musk Ambrette, a compound with a rich history and complex profile. Understanding its chemical properties and historical applications is key to appreciating its impact and the evolution of fragrance safety standards.

Musk Ambrette, identified by its CAS Number 83-66-9 and chemical formula C12H16N2O5, is classified as a synthetic nitro musk. Its physical appearance is typically described as pale yellowish to yellow granular crystals. Chemically, it exhibits a specific melting point range of 84-86°C and a boiling point of 185°C at 16mmHg. It is soluble in ether and slightly soluble in ethanol, but insoluble in water. These physical and chemical characteristics are crucial for its formulation and stability in various applications. The molecule's stability and scent profile made it a favored ingredient for many years.

The primary function of Musk Ambrette in perfumery was its role as a fixative. This means it helped to slow down the evaporation rate of more volatile fragrance components, thereby extending the scent's overall lifespan on the skin. Its characteristic sweet, heavy floral-musky odor provided a warm, tenacious note that complemented a wide range of other aroma chemicals. Its utility was evident in its widespread adoption across different product categories, from fine fragrances to household items.

The historical usage levels illustrate its importance. In perfumes, it could constitute up to 2.0% of the fragrance concentrate. In soaps, a mere 0.03% to 0.2% was often sufficient to impart its signature scent. This demonstrates its high potency and efficiency as a scent component and fixative. However, as scientific understanding of chemical safety advanced, concerns were raised about Musk Ambrette's potential adverse effects on human health. The International Fragrance Association (IFRA) subsequently issued guidelines restricting its use, prompting the industry to seek safer alternatives.

While current regulations limit its application, knowledge of Musk Ambrette's musk ambrette chemical properties remains valuable. It serves as a reference point for developing new musk compounds that can offer similar olfactory experiences without the associated health risks. The study of such historical ingredients allows for a deeper understanding of the challenges and innovations in the field of aroma chemistry, guiding future research and development at NINGBO INNO PHARMCHEM CO.,LTD. and the broader industry.