Exploring the Synthesis and Chemical Properties of 2,4-Dichloro-5-nitrophenol
2,4-Dichloro-5-nitrophenol, identified by its CAS number 39489-77-5, is a compound of significant interest in chemical synthesis and industrial applications. Its molecular formula, C6H3Cl2NO3, and molecular weight of approximately 208 g/mol, hint at its complex structure, featuring chlorine atoms and a nitro group on a phenolic ring. Typically appearing as a yellow solid, this compound possesses a melting point range of 96-98°C, indicating a stable solid form under standard conditions. Its assay typically exceeds 99.0%, highlighting its suitability for precise chemical reactions where purity is paramount.
The synthesis of 2,4-Dichloro-5-nitrophenol often involves the nitration of 2,4-dichlorophenol. This process, while seemingly straightforward, requires careful control of reaction conditions, including temperature and reagent addition rates, to ensure high yield and purity while minimizing the formation of unwanted byproducts. Industrial-scale production necessitates efficient methods for managing heat dissipation, recovering solvents like chloroform, and treating wastewater to comply with environmental regulations. The pursuit of green chemistry approaches has led to the development of more environmentally friendly synthetic routes, aiming to reduce hazardous waste.
Understanding the chemical properties of 2,4-Dichloro-5-nitrophenol is crucial for its effective utilization. Its density is around 1.7 g/cm³, and it exhibits a low vapor pressure, contributing to its stability. The compound's reactivity stems from the electron-withdrawing nature of the chlorine and nitro substituents, making the phenolic hydroxyl group acidic and susceptible to various reactions. This reactivity profile makes it a valuable intermediate in organic synthesis, particularly in the agrochemical sector.
Storage and handling are critical to maintain the quality of 2,4-Dichloro-5-nitrophenol. It is commonly packaged in 25kg drums and should be stored in a cool, dry, and well-ventilated environment with the container tightly sealed. This prevents moisture absorption and degradation, ensuring its assay remains at or above 99.0% and loss on drying below 0.5%. For manufacturers and suppliers, adhering to these guidelines is essential for delivering a consistent and high-quality product.
The compound's primary utility is as an intermediate in the synthesis of herbicides, such as Oxadiazon. This application underscores its importance in agriculture, where it contributes to effective weed management and crop protection. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-purity chemical intermediates like 2,4-Dichloro-5-nitrophenol, supporting industries that rely on precision chemistry for their advanced products.
Perspectives & Insights
Logic Thinker AI
“It is commonly packaged in 25kg drums and should be stored in a cool, dry, and well-ventilated environment with the container tightly sealed.”
Molecule Spark 2025
“This prevents moisture absorption and degradation, ensuring its assay remains at or above 99.”
Alpha Pioneer 01
“For manufacturers and suppliers, adhering to these guidelines is essential for delivering a consistent and high-quality product.”