Understanding Niclosamide CAS 50-65-7: Properties and Applications
NINGBO INNO PHARMCHEM CO.,LTD specializes in providing high-quality chemical compounds, including Niclosamide, identified by its CAS number 50-65-7. This compound is a fundamental element in both agricultural pest management and human/veterinary medicine, showcasing its versatility and importance. Understanding its physical and chemical properties is key to appreciating its wide-ranging applications.
Niclosamide typically appears as a light yellow or yellowish-white powder. It has a melting point in the range of 225-230°C, indicating its solid state at room temperature. While sparingly soluble in water, it exhibits better solubility in organic solvents like ethanol and acetone. These properties influence its formulation and how it is applied in different contexts. For instance, its low water solubility is advantageous in molluscicide applications, as it can remain effective in aquatic environments for a suitable duration without rapid dispersion.
The chemical structure of Niclosamide, a chlorinated salicylanilide, is responsible for its biological activity. Its primary mechanism of action involves inhibiting oxidative phosphorylation in the mitochondria of target organisms, effectively halting energy production. This makes it lethal to snails and effective against the metabolically active stages of tapeworms. The CAS 50-65-7 designation ensures precise identification of this chemical entity within the global supply chain.
When considering the purchase of Niclosamide, clients often inquire about various forms and concentrations. Niclosamide is available in different grades, including technical grades for agricultural use and GMP-certified grades for pharmaceutical applications. It is also formulated into various products, such as wettable powders (WP) and emulsifiable concentrates (EC) for agricultural spraying, and tablets for oral administration in medical treatments. NINGBO INNO PHARMCHEM CO.,LTD ensures the availability of Niclosamide that meets diverse formulation requirements, offering competitive pricing and reliable sourcing for clients worldwide.
Perspectives & Insights
Core Pioneer 24
“While sparingly soluble in water, it exhibits better solubility in organic solvents like ethanol and acetone.”
Silicon Explorer X
“These properties influence its formulation and how it is applied in different contexts.”
Quantum Catalyst AI
“For instance, its low water solubility is advantageous in molluscicide applications, as it can remain effective in aquatic environments for a suitable duration without rapid dispersion.”