5-Chlorosalicylaldehyde in Analytical Chemistry: Precision and Detection
NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of supplying critical chemical components for advanced analytical techniques, including the utilization of 5-Chlorosalicylaldehyde (CAS 635-93-8). This compound's reactive nature makes it an excellent tool for precise chemical analysis.
In UV-Visible spectrophotometry, 5-Chlorosalicylaldehyde acts as a chromogenic reagent. Its aldehyde group readily reacts with primary amines, such as amino acids, to form Schiff bases. These derivatives exhibit characteristic absorption peaks at specific wavelengths (λ max=430 nm), enabling sensitive detection and quantification of amines with detection limits as low as 0.1 μg/mL. This application is crucial for biochemical analysis and quality control in various industries.
The compound's utility extends to chromatography. By chemically bonding 5-Chlorosalicylaldehyde onto silica gel, specialized gas chromatography (GC) stationary phases can be developed. These phases offer high selectivity for separating chlorinated organic compounds, including chlorinated benzenes, achieving theoretical plate counts exceeding 5000/m, which indicates superior separation efficiency.
Furthermore, 5-Chlorosalicylaldehyde can be used to modify the surface of glassy carbon electrodes, creating sensitive electrochemical sensors. These sensors exhibit high sensitivity for detecting target analytes like dopamine within a specific pH range (e.g., pH 7.0). The detection linear range can extend from 1.0 × 10⁻⁷ to 1.0 × 10⁻⁴ M, with robust anti-interference capabilities, making it valuable for environmental monitoring and biomedical diagnostics.
The precision offered by analytical methods employing 5-Chlorosalicylaldehyde underscores its importance in scientific research and quality assurance. NINGBO INNO PHARMCHEM CO.,LTD. ensures the supply of high-purity 5-Chlorosalicylaldehyde to support these critical analytical applications. Accessing this compound through wholesale 5-chlorosalicylaldehyde purchase ensures cost-effectiveness for laboratories and research institutions.
Perspectives & Insights
Bio Analyst 88
“These sensors exhibit high sensitivity for detecting target analytes like dopamine within a specific pH range (e.”
Nano Seeker Pro
“0 × 10⁻⁴ M, with robust anti-interference capabilities, making it valuable for environmental monitoring and biomedical diagnostics.”
Data Reader 7
“The precision offered by analytical methods employing 5-Chlorosalicylaldehyde underscores its importance in scientific research and quality assurance.”