Bicine, identified by CAS number 150-25-4, is a member of the widely respected Good's Buffers, renowned for their utility in biological and biochemical research. As a zwitterionic compound, Bicine possesses both a positively and negatively charged group, which grants it excellent buffering capabilities over a specific pH range, typically between 7.6 and 9.0. This characteristic makes it particularly valuable for applications where precise pH control is essential for the stability and function of biological molecules and systems. Understanding the Bicine biological buffer pH range is key to unlocking its full potential in experimental settings.

When considering the Bicine uses in biochemistry, its stability and low metal-binding affinity are significant advantages. Compared to some other common buffers like HEPES, Bicine exhibits weaker interactions with metal ions, which can be crucial in experiments where metal ions might otherwise catalyze unwanted reactions or interfere with the biological process being studied. This property makes Bicine a preferred choice in sensitive biochemical assays and for studies involving metal-sensitive enzymes or proteins.

The substance is typically supplied as a white powder, offering convenience in preparation. Its solubility in water is high, further simplifying its incorporation into various buffer formulations. For researchers performing low-temperature biochemical research, Bicine provides consistent pH control, ensuring the integrity of samples and reactions that are often temperature-sensitive. This reliability is a major reason why many scientists actively seek to buy Bicine buffer.

Furthermore, Bicine's application extends to advanced techniques such as protein crystallization and chromatography. For protein crystallization, Bicine acts as a reliable pH stabilizer, which is indispensable for promoting the formation of well-ordered crystals necessary for structural analysis. In ion exchange chromatography, Bicine's consistent buffering capacity aids in the efficient separation and purification of proteins by maintaining optimal pH conditions throughout the chromatographic run. The reliable performance of Bicine in these demanding applications solidifies its position as a go-to buffer in many laboratories.

The chemical name for Bicine is N,N-Bis(2-hydroxyethyl)glycine, and its molecular formula is C6H13NO4, with a molecular weight of 163.17. The purity of Bicine is a critical factor for researchers, and NINGBO INNO PHARMCHEM CO.,LTD. ensures that their product meets high-quality standards, making it a trustworthy reagent for scientific endeavors. Whether for routine biochemical assays or specialized protein studies, Bicine remains a fundamental tool for ensuring experimental success.