Boosting PCR Accuracy: The Role of Bis-tetramethylammonium Oxalate
In the rapidly evolving field of molecular biology, the accuracy and sensitivity of Polymerase Chain Reaction (PCR) are paramount. Researchers are constantly seeking ways to improve these aspects, especially when dealing with low-template DNA or identifying rare mutations. One such compound that has shown significant promise in this area is Bis-tetramethylammonium oxalate, identified by its CAS number 98296-17-4. As a dedicated supplier of high-quality chemicals, NINGBO INNO PHARMCHEM CO.,LTD. understands the importance of such specialized reagents in driving scientific advancements.
Bis-tetramethylammonium oxalate functions as a PCR enhancer by selectively inhibiting the amplification of non-target DNA sequences, particularly wild-type fragments. This selective inhibition allows for a clearer and more sensitive detection of the desired mutated targets. Studies have indicated that even at low concentrations, this compound can drastically improve the threshold cycle values, making it an invaluable tool for applications such as early cancer detection or genetic anomaly identification. The ability to buy this crucial chemical reagent is essential for laboratories aiming to push the boundaries of molecular diagnostics.
The mechanism behind this enhancement is thought to be related to the interaction of tetramethylammonium ions with DNA, influencing primer binding and polymerase activity. By optimizing these interactions, Bis-tetramethylammonium oxalate helps to reduce false positives and negatives, leading to more reliable experimental results. For researchers looking to purchase this chemical, sourcing from a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures consistent quality and performance. Understanding the specific product details and its applications, such as acting as a Bis-tetramethylammonium oxalate PCR enhancer, is key to integrating it effectively into research protocols.
The price for such a specialized chemical can vary, but the investment in a reliable PCR enhancer like Bis-tetramethylammonium oxalate is often justified by the improved data quality and efficiency it provides. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing competitive pricing without compromising on the purity and efficacy of their products. Whether you are conducting cutting-edge research or developing new diagnostic assays, Bis-tetramethylammonium oxalate is a chemical reagent that can significantly elevate your PCR experiments.
In summary, the application of Bis-tetramethylammonium oxalate in PCR represents a significant step forward in molecular biology techniques. Its role as a selective DNA amplification enhancer makes it a critical component for many research endeavors. For those seeking to buy this product, NINGBO INNO PHARMCHEM CO.,LTD. stands ready to supply this vital chemical reagent, supporting your pursuit of scientific excellence.
Perspectives & Insights
Bio Analyst 88
“is committed to providing competitive pricing without compromising on the purity and efficacy of their products.”
Nano Seeker Pro
“Whether you are conducting cutting-edge research or developing new diagnostic assays, Bis-tetramethylammonium oxalate is a chemical reagent that can significantly elevate your PCR experiments.”
Data Reader 7
“In summary, the application of Bis-tetramethylammonium oxalate in PCR represents a significant step forward in molecular biology techniques.”