Understanding the fundamental chemical properties of specialized molecules is crucial for their effective application in research and industry. 11-Maleimidoundecanoic Acid (11-MUA) is a prime example, offering a unique combination of reactivity and structural versatility. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing scientists with detailed insights and high-quality supplies of such essential chemical intermediates.

11-Maleimidoundecanoic Acid, with the CAS number 57079-01-3, presents itself as a white crystalline powder. Its molecular formula, C15H23NO4, and a molecular weight of approximately 281.35 g/mol, hint at its structure: a ten-carbon chain terminated by a carboxylic acid group, and an 11-carbon chain terminating in a maleimide ring. The maleimide group is a cyclic imide that contains a double bond, making it highly susceptible to nucleophilic attack by thiols. This specific reactivity forms the basis of its widespread use as a cross-linker.

The chemical characteristics of 11-MUA make it an excellent choice for conjugation reactions. The maleimide functionality readily reacts with sulfhydryl groups in cysteine residues of proteins, forming a stable thioether linkage. This reaction is highly specific and efficient under mild conditions, which is vital when working with sensitive biomolecules. The carboxylic acid end of the molecule can be activated for coupling with amines, allowing it to be attached to various biomolecules or surfaces, thus enabling complex conjugates. For researchers looking to buy a reliable crosslinker, 11-MUA from NINGBO INNO PHARMCHEM CO.,LTD. is a strong candidate.

The applications of 11-Maleimidoundecanoic Acid span several scientific disciplines. In biotechnology, it is used for modifying proteins, creating antibody-drug conjugates (ADCs), and developing diagnostic assays. The compound's structure is also well-suited for its role as a linker in the synthesis of PROTACs, a rapidly growing area in drug discovery aimed at targeted protein degradation. The availability of high-purity 11-MUA from a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures that these advanced research applications can proceed with confidence.

Moreover, the compound's solubility in common organic solvents like methanol and chloroform facilitates its use in various reaction conditions. The company's dedication to quality control means that scientists can depend on the purity and consistency of the 11-Maleimidoundecanoic Acid they purchase, whether for small-scale laboratory experiments or larger synthesis projects. This detailed understanding of its chemical landscape makes 11-MUA an indispensable tool in modern chemical research.