Diethyl Acetylenedicarboxylate (CAS 762-21-0), also known as Diethyl 2-butynedioate, is a chemical compound characterized by its colorless to slightly yellow liquid appearance. Understanding its physical and chemical properties is crucial for its effective and safe utilization in various scientific applications. This compound is primarily recognized for its role as a versatile building block in organic synthesis, contributing to the creation of diverse chemical entities.

Key physical properties include a melting point of approximately 1-3°C, indicating it remains a liquid under typical laboratory conditions, and a density of around 1.06 g/mL. Its boiling point is recorded at 107-110°C at 11 mmHg. These properties, along with its molecular formula C8H10O4 and molecular weight of 170.16, define its behavior in chemical reactions and handling procedures. When researchers seek to buy Diethyl Acetylenedicarboxylate, these parameters are essential for selecting the appropriate grade and formulation.

From a chemical reactivity standpoint, the presence of the acetylenic triple bond activated by two ester groups makes Diethyl Acetylenedicarboxylate highly susceptible to nucleophilic additions and cycloaddition reactions. This reactivity is the foundation of its broad use in synthesizing complex organic molecules, including pharmaceutical intermediates and materials for advanced applications. The price of Diethyl Acetylenedicarboxylate often reflects the intricate synthesis required to produce it at high purity.

Safety considerations are paramount when working with any chemical, and Diethyl Acetylenedicarboxylate is no exception. While specific handling instructions should always be obtained from the Safety Data Sheet (SDS), general guidelines include working in a well-ventilated area, wearing appropriate personal protective equipment (PPE) such as gloves and eye protection, and avoiding inhalation or skin contact. Proper storage, often recommended at 2-8°C or 4°C as per manufacturer specifications, is also vital to maintain its stability and efficacy. NINGBO INNO PHARMCHEM CO.,LTD. emphasizes adherence to safety protocols and provides necessary documentation to ensure responsible handling of their Diethyl Acetylenedicarboxylate supply.