Understanding the fundamental chemical properties and synthesis routes of key intermediates is crucial for any chemist or industry professional. Oleoyl Chloride (CAS: 112-77-6) is a prime example of such a compound, widely recognized for its versatility in organic synthesis. From its characteristic appearance to its reactivity profile, Oleoyl Chloride serves as a vital component in the production of numerous valuable chemical products. NINGBO INNO PHARMCHEM CO.,LTD. offers insights into this important intermediate.

Chemically, Oleoyl Chloride is the acyl chloride derivative of oleic acid. Its molecular formula is C18H33ClO, and it possesses a molecular weight of approximately 300.91 g/mol. A defining feature is its acyl chloride functional group (-COCl), which is highly reactive towards nucleophiles. This reactivity is the basis for its widespread use in acylation reactions. Typically, Oleoyl Chloride appears as a transparent, colorless to light beige liquid, with a purity often exceeding 99.0%. Its physical state and clarity are important indicators of its quality and suitability for sensitive chemical processes.

The synthesis of Oleoyl Chloride generally involves the reaction of oleic acid with chlorinating agents. Common methods include treatment with thionyl chloride (SOCl2), phosphorus trichloride (PCl3), or oxalyl chloride ((COCl)2). These reactions convert the carboxylic acid group of oleic acid into the more reactive acyl chloride group. The choice of chlorinating agent and reaction conditions can influence the yield and purity of the final product. Ensuring anhydrous conditions throughout the synthesis and purification process is critical, as Oleoyl Chloride is susceptible to hydrolysis.

The oleoyl chloride applications are extensive and diverse. As previously mentioned, its primary use is as an intermediate in the synthesis of surfactants. By reacting with alcohols and amines, it forms esters and amides, which are the backbone of many detergent, emulsifying, and wetting agents. These products are essential in a vast array of consumer goods and industrial applications, from cleaning products to personal care items.

Beyond surfactants, Oleoyl Chloride is a critical pharmaceutical intermediate. Its ability to introduce the long oleoyl chain into molecules can modify pharmacokinetic properties, enhance solubility, or facilitate targeted drug delivery. This makes it invaluable in the development of new therapeutics and specialized drug formulations. The chemical industry also benefits from its use in creating various fatty acid derivatives used in lubricants, polymers, and cosmetics, where its properties contribute to enhanced performance and stability.

For professionals looking to procure this essential chemical, sourcing high-quality Oleoyl Chloride is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying Oleoyl Chloride that meets stringent specifications, ensuring reliable performance in your synthesis processes. Whether you are focused on surfactant production or seeking specific pharmaceutical intermediates, our commitment to quality and purity makes us an ideal partner. Understanding the oleoyl chloride properties and synthesis methods allows for informed decision-making when selecting suppliers and optimizing reaction protocols.

In summary, Oleoyl Chloride is a compound of significant chemical importance, characterized by its reactivity, purity, and broad applicability. Its synthesis from oleic acid and its role as a versatile intermediate for surfactants, pharmaceuticals, and other industrial products highlight its value in modern chemistry. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this essential chemical to support your manufacturing and research endeavors.