Chemical Properties and Synthesis Routes of 1-Bromo-2-chloro-3-fluoro-4-iodobenzene
Understanding the detailed chemical and physical properties of an intermediate is fundamental to its successful application in synthesis. 1-Bromo-2-chloro-3-fluoro-4-iodobenzene (CAS 1000573-03-4) is a prime example of such a compound, offering a unique combination of features that make it highly sought after in the fine chemical industry. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing comprehensive information on this versatile molecule, from its intrinsic properties to its synthetic pathways.
The molecular formula of 1-Bromo-2-chloro-3-fluoro-4-iodobenzene is C6H2BrClFI, with a molecular weight of 335.340. Its exact mass is precisely 333.805695, a critical parameter for analytical chemists. The compound exhibits a density of 2.3±0.1 g/cm³ and a boiling point of 285.7±35.0 °C at 760 mmHg. Its flash point of 126.6±25.9 °C suggests moderate flammability, requiring careful handling. The LogP value of 4.07 indicates significant lipophilicity, which is advantageous for solubility in organic solvents commonly used in synthesis. The vapor pressure is low, at 0.0±0.6 mmHg at 25°C, and its refractive index is 1.639, providing valuable optical characteristics.
As a pharmaceutical intermediate, the precise synthesis and purity of 1-bromo-2-chloro-3-fluoro-4-iodobenzene are paramount. Chemists can synthesize 1-bromo-2-chloro-3-fluoro-4-iodobenzene through various multi-step processes, often involving halogenation reactions on substituted benzene rings. The presence of multiple reactive halogen sites allows for sequential, selective functionalization, making it a highly desirable organic synthesis intermediate. When seeking to buy this compound, partnering with a reputable 1-bromo-2-chloro-3-fluoro-4-iodobenzene manufacturer China ensures that the product meets the rigorous purity requirements (≥97.0%) necessary for pharmaceutical applications.
The industrial significance of this compound cannot be overstated. Its ability to undergo selective cross-coupling reactions makes it a cornerstone in the construction of complex organic molecules used in drug discovery and development. The demand for such high-value intermediates is met by experienced manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., who leverage advanced chemical engineering and quality control measures. Our commitment as a leading supplier ensures that researchers and manufacturers have access to the reliable materials needed to drive innovation in the pharmaceutical sector and beyond. We are dedicated to providing detailed specifications and supporting our clients through every stage of their research and production.
Perspectives & Insights
Quantum Pioneer 24
“1-Bromo-2-chloro-3-fluoro-4-iodobenzene (CAS 1000573-03-4) is a prime example of such a compound, offering a unique combination of features that make it highly sought after in the fine chemical industry.”
Bio Explorer X
“is dedicated to providing comprehensive information on this versatile molecule, from its intrinsic properties to its synthetic pathways.”
Nano Catalyst AI
“The molecular formula of 1-Bromo-2-chloro-3-fluoro-4-iodobenzene is C6H2BrClFI, with a molecular weight of 335.”