2-Bromo-5-chloroaniline, identified by its CAS number 823-57-4, is a fundamental organic intermediate that underpins numerous industrial chemical processes. Its specific arrangement of bromine and chlorine atoms on an aniline backbone bestows upon it a unique reactivity profile, making it indispensable in a wide range of synthetic applications. Understanding its chemical and physical characteristics is key to leveraging its full potential.

Physically, 2-Bromo-5-chloroaniline is typically presented as a light yellow to light brown powder. Its molecular formula, C6H5BrClN, and molecular weight of 206.46800 provide essential identifiers. Key physical properties include a density of 1.722 g/cm³, a melting point of 38ºC, and a boiling point of 128ºC. The flash point of 114.5ºC suggests a moderate flammability risk, necessitating standard safety precautions during handling. Its index of refraction is recorded at 1.638.

Chemically, the compound is a versatile intermediate primarily used in organic synthesis. The presence of the amine group (-NH2) and the halogen substituents (Br and Cl) allows for diverse reactions. For example, it can be subjected to substitution reactions, coupling reactions (like Suzuki and Ullman couplings), and functional group transformations. These reactions are critical for building complex molecules used in pharmaceuticals, agrochemicals, and specialized dyes.

One significant application involves its role in the synthesis of compounds for inhibiting c-myc/max/DNA complex formation, highlighting its importance in biochemical research and drug development. It also serves as a precursor for creating pyrimidinium chlorides and other nitrogen-containing heterocycles. Researchers continually explore new synthetic routes involving 2-Bromo-5-chloroaniline to develop novel materials with tailored properties.

For industrial users, maintaining the quality of 2-Bromo-5-chloroaniline is paramount. Suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensure high purity levels (≥99.0%) and low moisture content (≤0.2%), adhering to strict quality specifications. Proper storage in a cool, ventilated area is recommended to preserve its integrity. As industries continue to innovate, the demand for reliable sources to buy 2-Bromo-5-chloroaniline remains high, underscoring its sustained value in chemical manufacturing.