Sodium 1-Heptanesulfonate is a versatile chemical compound with significant applications, particularly in the field of analytical chemistry. As an anionic surfactant, it possesses unique properties that make it highly valuable as an ion-pairing reagent in High-Performance Liquid Chromatography (HPLC). NINGBO INNO PHARMCHEM CO.,LTD. provides this essential compound, enabling researchers to achieve precise separations and analyses.

The chemical structure of Sodium 1-Heptanesulfonate consists of a seven-carbon alkyl chain (heptane) attached to a sulfonate group, with a sodium counter-ion. This amphipathic nature, having both a hydrophobic tail and a hydrophilic head, is fundamental to its functionality. In HPLC, the sulfonate group acts as the negatively charged component that pairs with positively charged analytes, forming a less polar complex. This process is key to its effectiveness in the analysis of peptides and proteins, where the charged nature of amino acid residues can be leveraged for separation.

A primary benefit of using Sodium 1-Heptanesulfonate is its ability to improve HPLC separation of basic analytes. By forming an ion pair, the reagent effectively neutralizes the positive charge of basic compounds, thereby increasing their interaction with the non-polar stationary phase of the HPLC column. This leads to better retention, sharper peaks, and ultimately, improved resolution. This makes it a critical reagent for many complex analyses, including those involving biologically active molecules.

The efficacy of analytical methods often hinges on the purity of the reagents used. Sodium 1-Heptanesulfonate is available in high purity grades, ensuring reliable and reproducible results. When laboratories buy Sodium 1-Heptanesulfonate, they are seeking a high purity ion pairing reagent that will not introduce artifacts into their data. Its consistent chemical properties, often identified by its CAS number, sodium heptane sulfonate CAS 22767-50-6, make it a trusted component in analytical workflows.

Beyond its role as an ion pairing reagent for peptide analysis, Sodium 1-Heptanesulfonate also serves as an anionic detergent. While this application is distinct from its chromatographic use, it underscores the compound's chemical versatility. In HPLC, its consistent performance in the analysis of proteins using ion pair chromatography makes it a preferred choice for researchers aiming for high-resolution separations. The reagent's solubility in water also simplifies its preparation in mobile phases.

In conclusion, Sodium 1-Heptanesulfonate is a vital chemical compound that enhances analytical capabilities, particularly in HPLC. Its ability to improve the separation of charged analytes, coupled with its high purity, makes it an essential tool for researchers in various scientific fields. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing the scientific community with high-quality reagents that drive discovery and innovation in analytical science.