Exploring the Chemical Properties and Handling of Tetraethylene Glycol Ditosylate
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing researchers with high-quality chemical compounds, and understanding their properties is essential for effective use. Tetraethylene Glycol Ditosylate (CAS 37860-51-8) is a compound characterized by its specific chemical structure and physical attributes that dictate its applications and handling requirements.
Physically, Tetraethylene Glycol Ditosylate presents as a white solid. This form factor makes it relatively easy to handle, weigh, and store compared to liquids, especially in laboratory settings. The specified purity of 97% is a critical parameter, ensuring that the compound is suitable for sensitive applications in pharmaceutical research and advanced organic synthesis, where impurities can lead to unwanted side reactions or reduced yields.
Chemically, the presence of two tosylate (p-toluenesulfonate) groups is its defining feature. Tosylates are excellent leaving groups, meaning they are easily displaced by nucleophiles during chemical reactions. This property makes Tetraethylene Glycol Ditosylate an exceptionally useful intermediate for a variety of synthetic transformations. The flexible tetraethylene glycol chain provides spacing and solubility characteristics that are often leveraged in the design of linkers for bioconjugates or in the synthesis of complex molecules where chain length and flexibility are important design considerations.
When handling Tetraethylene Glycol Ditosylate, standard laboratory safety protocols should be observed. As with many fine chemicals, it is recommended to avoid inhalation, ingestion, and prolonged skin contact. Safety data sheets (SDS) should be consulted for detailed handling, storage, and disposal information. NINGBO INNO PHARMCHEM CO.,LTD. typically recommends storing such compounds in a cool, dry place, often in a tightly sealed container to prevent moisture absorption and degradation.
The versatility of Tetraethylene Glycol Ditosylate in applications ranging from PROTAC synthesis to general organic chemistry makes it a valuable reagent. Researchers seeking this compound can trust NINGBO INNO PHARMCHEM CO.,LTD. for a reliable supply of high-purity material, ensuring that their experiments and synthetic processes are built on a solid chemical foundation.
Perspectives & Insights
Chem Catalyst Pro
“This property makes Tetraethylene Glycol Ditosylate an exceptionally useful intermediate for a variety of synthetic transformations.”
Agile Thinker 7
“The flexible tetraethylene glycol chain provides spacing and solubility characteristics that are often leveraged in the design of linkers for bioconjugates or in the synthesis of complex molecules where chain length and flexibility are important design considerations.”
Logic Spark 24
“When handling Tetraethylene Glycol Ditosylate, standard laboratory safety protocols should be observed.”