Tetraethylene Glycol Ditosylate: A Key Intermediate in Modern Chemistry
Explore the synthesis, applications, and benefits of this vital compound for your research and development.
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Tetraethylene Glycol Ditosylate
Tetraethylene Glycol Ditosylate (CAS 37860-51-8) is a critical chemical intermediate characterized by its 97% purity and appearance as a white solid. Its molecular structure and the presence of tosylate groups make it an excellent leaving group for nucleophilic substitution reactions, driving its utility in advanced organic synthesis.
- Unlock new possibilities in drug discovery with the unique properties of high purity tetraethylene glycol ditosylate. This compound serves as a crucial component in the development of advanced therapeutic modalities.
- Leverage the power of PROTAC linker tetraethylene glycol ditosylate for targeted protein degradation. Its specific chemical structure facilitates the creation of novel PROTAC molecules.
- Enhance your bioconjugation strategies using tetraethylene glycol ditosylate as an ADC linker. This chemical intermediate is instrumental in the precise attachment of payloads to antibodies.
- Achieve reliable and efficient outcomes in chemical synthesis with tetraethylene glycol ditosylate. Its consistent purity ensures predictable reaction performance.
Key Advantages of Tetraethylene Glycol Ditosylate
Versatile Linker Capability
Tetraethylene glycol ditosylate is indispensable as a linker in both Antibody-Drug Conjugates (ADCs) and Proteolysis Targeting Chimeras (PROTACs), facilitating precise molecular construction for therapeutic applications.
Excellent Leaving Group Properties
The tosylate functional groups provide superior leaving group characteristics, enabling efficient nucleophilic substitution reactions critical for complex organic synthesis pathways.
High Purity for Reproducible Results
With a purity of 97%, tetraethylene glycol ditosylate guarantees reproducible and reliable results in demanding chemical synthesis and research projects.
Key Applications
Bioconjugation
As an ADC linker, tetraethylene glycol ditosylate plays a vital role in creating targeted therapies by linking cytotoxic agents to antibodies, a process crucial in modern cancer treatment.
PROTAC Synthesis
The compound is a key building block for PROTACs, enabling the development of novel therapeutics that harness the cell's natural protein degradation machinery.
Organic Synthesis Intermediate
Its reactivity makes tetraethylene glycol ditosylate a valuable intermediate in a wide array of organic synthesis projects, facilitating the creation of complex molecules.
Drug Discovery Research
Researchers utilize tetraethylene glycol ditosylate to explore new chemical entities and optimize lead compounds in the pursuit of novel pharmaceuticals.