To fully appreciate the utility of Ethyl 2-Oximinooxamate (CAS 10489-74-4), it is essential to understand its underlying chemical properties and reactivity. This white crystalline compound, supplied by NINGBO INNO PHARMCHEM CO.,LTD., possesses unique structural features that dictate its behavior in various chemical transformations, making it a valuable tool in organic synthesis.

The core structure of Ethyl 2-Oximinooxamate features an oxime group (-C=N-OH) and an ester group (-COO-). The oxime functionality is particularly notable for its acidity and nucleophilic/electrophilic potential. The nitrogen atom in the oxime can participate in coordination with metal ions, forming stable complexes, which is relevant in coordination chemistry. The hydroxyl group on the oxime also imparts hydrogen-bonding capabilities.

The compound's reactivity is further influenced by resonance stabilization within the oxamate moiety. This electronic delocalization contributes to its stability, especially when compared to some other common reagents. The ester group can undergo hydrolysis or transesterification reactions, and the overall molecule can participate in various addition and substitution reactions. Understanding these aspects is crucial for chemists seeking to utilize Ethyl 2-Oximinooxamate reactivity effectively.

In terms of stability, Ethyl 2-Oximinooxamate is generally considered more stable than older benzotriazole-based additives, particularly concerning thermal decomposition. This improved safety profile is a significant advantage for laboratory use. Researchers often refer to it by its common abbreviation, OxymaPure, especially when discussing its role as a peptide coupling additive. The exploration of OxymaPure chemical properties has led to its widespread adoption.

NINGBO INNO PHARMCHEM CO.,LTD. provides high-purity Ethyl 2-Oximinooxamate, ensuring consistent performance in synthesis. The company’s commitment to quality supports scientists in leveraging the compound’s inherent reactivity for diverse applications, from peptide synthesis to the creation of novel functional molecules. By understanding the fundamental chemical properties of CAS 10489-74-4, researchers can unlock its full potential in their work.