Exploring the Chemical Reactivity of 3,5-Dichloro-2-iodopyrazine for Synthesis
Understanding the chemical reactivity of specialized compounds is paramount for successful organic synthesis. NINGBO INNO PHARMCHEM CO.,LTD. provides researchers and industrial chemists with essential building blocks, and 3,5-dichloro-2-iodopyrazine is a prime example of a versatile molecule offering rich reactivity. This compound, identified by its CAS number 136866-30-3, is a cornerstone for chemists looking to construct complex molecular architectures, particularly in the pharmaceutical and fine chemical sectors.
The structure of 3,5-dichloro-2-iodopyrazine is key to its synthetic utility. The presence of three halogen atoms – two chlorine atoms and one iodine atom – on the pyrazine ring provides multiple reactive sites for functionalization. The iodine atom, being a good leaving group, is particularly amenable to various transition metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Stille, and Sonogashira couplings. These reactions are fundamental in modern organic synthesis for forming new carbon-carbon bonds, allowing for the efficient introduction of diverse substituents. When planning to buy or purchase chemicals for synthesis, the reactivity profile is a major consideration.
Beyond cross-coupling, the chlorine atoms on the pyrazine ring can also participate in nucleophilic aromatic substitution (SNAr) reactions. This allows for the introduction of nitrogen, oxygen, or sulfur nucleophiles, further expanding the range of accessible derivatives. The ability to selectively functionalize different positions on the ring makes 3,5-dichloro-2-iodopyrazine an extremely valuable intermediate for creating libraries of compounds or for targeted synthesis of specific molecules. Its role as a pharmaceutical raw intermediate is thus well-established.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying chemists with high-purity materials that ensure predictable and reproducible reaction outcomes. Our rigorous quality control processes for compounds like 3,5-dichloro-2-iodopyrazine guarantee that you receive a product that meets the high demands of advanced organic synthesis. For those looking to procure essential chemicals, understanding the product's price and the supplier's commitment to quality is crucial. We aim to be your trusted source for all your chemical synthesis needs.
In summary, the rich chemical reactivity of 3,5-dichloro-2-iodopyrazine makes it an invaluable tool for organic synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is proud to offer this critical building block, supporting innovation and advancements in chemical research and development worldwide.
Perspectives & Insights
Molecule Vision 7
“The iodine atom, being a good leaving group, is particularly amenable to various transition metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Stille, and Sonogashira couplings.”
Alpha Origin 24
“These reactions are fundamental in modern organic synthesis for forming new carbon-carbon bonds, allowing for the efficient introduction of diverse substituents.”
Future Analyst X
“When planning to buy or purchase chemicals for synthesis, the reactivity profile is a major consideration.”