1-Iodopentane, known by its CAS Registry Number 628-17-1, is an organic compound that plays a significant role in various chemical processes. This iodoalkane, a derivative of pentane, is characterized by a terminal iodine atom, which imparts specific reactivity and physical properties making it valuable in both laboratory research and industrial applications. Understanding its chemistry is key to leveraging its full potential.

Physically, 1-Iodopentane is described as a clear, colorless to yellow liquid with a gasoline-like odor. Its molecular formula is C5H11I, giving it a molecular weight of approximately 198.05 g/mol. Key physical properties include a melting point of -85.6 °C and a boiling point typically in the range of 154-155 °C. Its density is around 1.517 g/ml at 25 °C. The compound is generally insoluble in water but soluble in common organic solvents, which is a crucial characteristic for its use as a solvent in various organic reactions.

In terms of synthesis, 1-Iodopentane can be prepared through several methods. A common approach involves the reaction of 1-pentanol with phosphorus triiodide (PI3) or a combination of iodine and red phosphorus. Another method involves the free-radical iodination of pentane, though this often leads to a mixture of isomers. The selection of a synthesis route typically depends on factors such as desired purity, yield, and available reagents. The ability to efficiently buy 1-Iodopentane from specialized suppliers ensures access to high-quality material for research and manufacturing.

The applications of 1-Iodopentane are broad. Primarily, it functions as a solvent in various chemical reactions and analytical techniques. Its reactivity as an iodoalkane also makes it a valuable intermediate in organic synthesis. It can be used in nucleophilic substitution reactions to introduce the pentyl group into other molecules, which is important in the synthesis of pharmaceuticals, fragrances, and other fine chemicals. Its specific applications can range from being a reagent in Grignard reactions to participating in radical chain reactions.

Safety considerations are paramount when handling 1-Iodopentane. It is a flammable liquid and requires storage in cool, well-ventilated areas, away from ignition sources. Proper personal protective equipment, including gloves, eye protection, and lab coats, should always be worn. Its irritant properties necessitate working in well-ventilated areas, such as fume hoods, to avoid inhalation of vapors and skin or eye contact.

In summary, 1-Iodopentane (CAS 628-17-1) is a versatile compound with well-defined physical and chemical properties. Its utility as a solvent and an intermediate in organic synthesis makes it a valuable chemical for researchers and industry professionals. Adhering to safety guidelines and understanding its chemical behavior are essential for its effective and responsible use.