The Chemistry Behind 2-Fluoro-4-nitroanisole: Properties and Synthesis Pathways
The intricate world of organic chemistry relies on a diverse array of building blocks, and 2-Fluoro-4-nitroanisole (CAS 455-93-6) stands out as a particularly valuable intermediate. NINGBO INNO PHARMCHEM CO.,LTD. is pleased to provide insights into the chemical characteristics and synthesis pathways of this important compound, crucial for numerous industrial and research applications.
2-Fluoro-4-nitroanisole, also known by synonyms such as 2-fluoro-1-methoxy-4-nitrobenzene, possesses a molecular formula of C7H6FNO3 and a molecular weight of approximately 171.13 g/mol. Its physical properties, typically described as a white to light yellow crystalline powder, are complemented by a melting point in the range of 103-105 °C. This solid form at room temperature simplifies handling and storage, making it a practical choice for chemical synthesis operations. The predictable physical form ensures that when you buy 2-fluoro-4-nitroanisole, you receive a consistent and manageable product.
The chemical reactivity of 2-fluoro-4-nitroanisole is largely attributed to the electron-withdrawing nature of the nitro group and the electron-donating effect of the methoxy group, alongside the presence of the fluorine atom. These features allow for selective reactions, such as nucleophilic aromatic substitution, making it a versatile intermediate for creating more complex molecules. The strategic positioning of these functional groups on the benzene ring enables its use in a wide range of organic synthesis building block applications.
Understanding the synthesis of 2-fluoro-4-nitroanisole is also important for appreciating its role in the chemical supply chain. While specific industrial synthesis routes can vary, common approaches involve the nitration and subsequent methoxylation of fluorinated benzene derivatives. The efficiency and yield of these processes directly impact the availability and price of 2-fluoro-4-nitroanisole, influencing its procurement by researchers and manufacturers.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality chemical intermediates. Our role as a supplier of essential compounds like 2-fluoro-4-nitroanisole supports the advancement of chemical research and product development. We work with leading 2-fluoro-4-nitroanisole manufacturers to ensure that the products we offer meet stringent purity and quality specifications.
In conclusion, the chemical properties and synthesis pathways of 2-fluoro-4-nitroanisole make it a cornerstone intermediate for various scientific and industrial endeavors. Its utility as a chemical synthesis intermediate, particularly in the pharmaceutical sector, highlights its enduring importance in the chemical industry.
Perspectives & Insights
Future Origin 2025
“Understanding the synthesis of 2-fluoro-4-nitroanisole is also important for appreciating its role in the chemical supply chain.”
Core Analyst 01
“While specific industrial synthesis routes can vary, common approaches involve the nitration and subsequent methoxylation of fluorinated benzene derivatives.”
Silicon Seeker One
“The efficiency and yield of these processes directly impact the availability and price of 2-fluoro-4-nitroanisole, influencing its procurement by researchers and manufacturers.”