1-Chlorobutane, identified by CAS number 109-69-3, is a foundational chemical in organic synthesis, valued for its utility as a solvent and a reactive intermediate. NINGBO INNO PHARMCHEM CO.,LTD. provides this compound, emphasizing both its chemical versatility and the importance of adhering to stringent safety protocols for its handling and storage. The synthesis of 1-Chlorobutane typically involves the reaction of n-butanol with hydrogen chloride or hydrochloric acid, often facilitated by catalysts to improve yields and purity. Manufacturers focus on achieving high purity levels, frequently above 99%, to meet the demanding requirements of downstream applications.

The core chemical reaction for producing 1-Chlorobutane involves the nucleophilic substitution of the hydroxyl group in n-butanol by a chloride ion. This process can be achieved through various methods, including direct reaction with HCl gas or concentrated hydrochloric acid, sometimes in the presence of catalysts like zinc chloride. The optimization of these synthesis routes aims to reduce by-products, increase efficiency, and ensure environmental compliance.

One of the most significant applications of 1-Chlorobutane is its role as a key intermediate in the production of Myclobutanil, a widely used fungicide. This application highlights the compound's importance in the agricultural sector, contributing to effective crop protection strategies. The ability of 1-Chlorobutane to act as a butylating agent is central to its utility in creating complex agrochemical molecules.

In the pharmaceutical industry, 1-Chlorobutane serves as a valuable intermediate for synthesizing various APIs and fine chemicals. Its reactivity allows for the introduction of the butyl group, a common structural feature in many pharmaceutical compounds. The demand for high-purity 1-chlorobutane ensures the quality and effectiveness of these life-saving medications.

Safe handling of 1-Chlorobutane is paramount due to its high flammability. Its vapors can form explosive mixtures with air, and it possesses a low flash point. Therefore, proper storage in cool, well-ventilated areas, away from ignition sources, is essential. Industrial practices include grounding and bonding containers to prevent static electricity build-up, and using explosion-proof equipment. Understanding the properties of 1-chlorobutane CAS 109-69-3 is crucial for safe operational procedures.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying reliable, high-quality 1-Chlorobutane, supporting its clients in leveraging this essential chemical safely and efficiently in their synthesis and manufacturing processes.