NINGBO INNO PHARMCHEM CO.,LTD. offers an in-depth comparison between N-Isopropylbenzylamine (CAS 102-97-6) and methamphetamine, two compounds that, despite structural similarities, exhibit distinct chemical properties, biological activities, and regulatory statuses. This comparative analysis is vital for accurate identification, especially in forensic and toxicological contexts.

Structurally, both N-Isopropylbenzylamine and methamphetamine are secondary amines with the molecular formula C10H15N. However, they differ in their substituent arrangements. Methamphetamine features a methyl group on the alpha-carbon, while N-Isopropylbenzylamine has an isopropyl group attached to the nitrogen atom. This subtle difference leads to significant variations in their physical and chemical behaviors. The market price of N-Isopropylbenzylamine can also differ from that of regulated substances.

From an analytical perspective, distinguishing between N-Isopropylbenzylamine and methamphetamine can be challenging. Conventional gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) methods may exhibit overlapping retention times and mass spectral fragments due to their structural similarity. Specialized chromatographic columns and optimized tandem mass spectrometry (MS/MS) transitions are often required for definitive differentiation, ensuring accurate identification when researchers purchase N-Isopropylbenzylamine.

Biologically, the differences are more pronounced. Methamphetamine is a potent central nervous system stimulant known for its high abuse potential and addictive properties, primarily acting through the dopaminergic and noradrenergic systems. In contrast, N-Isopropylbenzylamine is not known to possess significant stimulant effects of its own. However, toxicological studies suggest it can induce neuronal cell death via nitric oxide overproduction, highlighting a different mechanism of toxicity. While N-Isopropylbenzylamine has been investigated for conditioned place preference in animal models, suggesting some reinforcing properties, these are generally considered less potent than those of methamphetamine.

The forensic and regulatory implications of these differences are significant. Due to its use as an adulterant in illicit drug preparations, the identification and control of N-Isopropylbenzylamine are crucial. NINGBO INNO PHARMCHEM CO.,LTD. provides high-quality N-Isopropylbenzylamine for legitimate scientific and industrial applications, emphasizing the importance of responsible purchasing and adherence to all applicable regulations. Understanding these distinctions ensures that researchers and industries can effectively utilize N-Isopropylbenzylamine while mitigating associated risks.