Ethyl 8-bromooctanoate (CAS: 29823-21-0, C10H19BrO2) is a compound of considerable interest within the chemical industry, particularly for its applications in organic synthesis, pharmaceuticals, and agrochemicals. This article provides an overview of its key chemical properties, common synthesis routes, and current market trends, offering valuable insights for professionals in these fields.

The chemical properties of ethyl 8-bromooctanoate are central to its utility. It is described as a colorless to light yellow liquid, with a density of 1.194 g/cm³ and a boiling point of 267.1°C at 760 mmHg. The presence of a bromine atom at the eighth carbon position of the octanoate chain makes it highly reactive, particularly in nucleophilic substitution and coupling reactions, which are fundamental processes in organic synthesis. The ester functionality also contributes to its solubility and reactivity profile.

Understanding the synthesis of ethyl 8-bromooctanoate is crucial for both production and research. The most direct method involves the esterification of 8-bromooctanoic acid with ethanol, typically catalyzed by a strong acid like sulfuric acid. This process is efficient and yields high-purity product, essential for its demanding applications. Alternative routes may start from precursors like 1,6-dibromohexane, involving several intermediate steps before achieving the final ester.

As a vital pharmaceutical intermediate, ethyl 8-bromooctanoate plays a critical role in the creation of various drug molecules. Its structure can be elaborated to form active pharmaceutical ingredients (APIs) with diverse therapeutic properties. The demand for this compound in drug discovery and development remains strong, driven by the continuous need for novel treatments. Pharmaceutical manufacturers rely on consistent supply and high purity when they buy ethyl 8-bromooctanoate.

In the agrochemical sector, ethyl 8-bromooctanoate serves as a key component in agrochemical synthesis. It is utilized in the production of pesticides, herbicides, and insecticides, contributing to crop protection and improved agricultural yields. The compound’s structural versatility allows for the design of agrochemicals that are both effective and environmentally conscious.

Market trends indicate a steady demand for ethyl 8-bromooctanoate, largely influenced by growth in the pharmaceutical and agrochemical sectors. Professionals seeking to source this chemical will find various suppliers and manufacturers. When considering the price of ethyl 8-bromooctanoate, it’s important to factor in purity, quantity, and the supplier's reputation. NINGBO INNO PHARMCHEM CO.,LTD. is a recognized ethyl 8-bromooctanoate manufacturer committed to quality and innovation in chemical supply. Engaging with comprehensive market analyses can further inform procurement strategies.