Exploring the Chemical Properties and Synthesis of 1-Bromo-2-methoxyethane
Understanding the fundamental properties and synthesis routes of key chemical intermediates is crucial for their effective utilization in industrial and research settings. 1-Bromo-2-methoxyethane, identified by CAS number 6482-24-2, is a significant organic compound whose chemical and physical characteristics make it a valuable player in various synthetic processes. NINGBO INNO PHARMCHEM CO.,LTD. is a leading provider of this essential chemical, ensuring high quality and consistency for its users.
The chemical name, 1-Bromo-2-methoxyethane, accurately describes its structure, a three-carbon chain with a bromine atom on one end and a methoxy group on the adjacent carbon. Its molecular formula is C₃H₇BrO, with a molecular weight of approximately 138.99 g/mol. Physically, it is typically described as a colorless to light yellow liquid. Its density is around 1.479 g/cm³, and it has a relatively low boiling point, often reported in the range of 40-41°C at reduced pressure. The flash point of 28.3°C indicates that it is a flammable liquid, necessitating careful handling and storage away from ignition sources. These properties are critical for chemists and engineers when designing reaction conditions, purification protocols, and ensuring safe laboratory practices. Researchers can investigate the purchase of this compound to utilize these properties.
The synthesis of 1-Bromo-2-methoxyethane is commonly achieved through the bromination of 2-methoxyethanol. One established method involves the use of phosphorus tribromide (PBr₃) as both a Lewis acid and brominating agent. This reaction typically proceeds by protonating the hydroxyl group of 2-methoxyethanol, forming an intermediate that is subsequently displaced by a bromide ion. Reaction conditions, such as temperature (60–70°C) and stoichiometry of PBr₃ (1.0–1.2 equiv), are key to achieving high yields (85–90%) and purity. Another approach utilizes dibromosulfoxide (Br₂SO) in the presence of N,N-dimethylacetamide (DMA) as a catalyst, offering good regioselectivity under milder conditions. The choice of synthesis method often depends on desired yield, purity requirements, and available resources. For those looking to buy 1-Bromo-2-methoxyethane, understanding these synthesis details helps in appreciating the quality and cost of the product.
The applications of 1-Bromo-2-methoxyethane are diverse and impactful. It serves as a vital intermediate in organic synthesis, enabling the creation of a wide range of organic compounds. Its significance is particularly pronounced in the pharmaceutical industry, where it is used in the synthesis of drugs like Erlotinib, an anti-cancer agent. The compound's reactivity also makes it valuable in the agrochemical sector and for producing specialty chemicals. NINGBO INNO PHARMCHEM CO.,LTD. ensures that the 1-Bromo-2-methoxyethane supplied meets rigorous quality standards, making it a reliable choice for researchers and manufacturers. Proper storage in a clean, dry, and cool place, away from sunlight and rain, is crucial to maintain its chemical integrity.
In conclusion, 1-Bromo-2-methoxyethane is a versatile and essential chemical intermediate. Its well-defined physical and chemical properties, coupled with efficient synthesis methods, make it indispensable for numerous applications. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this compound to the scientific community, supporting advancements in pharmaceuticals, agrochemicals, and organic synthesis. Exploring the purchase of this compound can be a strategic step for many research and development projects.
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