Understanding the fundamental chemical properties and synthesis pathways of key intermediates is crucial for their effective application. 4,4'-(Hexafluoroisopropylidene)diphthalic Acid (CAS 3016-76-0) is a prime example of such a compound, valued for its unique molecular architecture and reactivity. NINGBO INNO PHARMCHEM CO., LTD., as a producer of this fine chemical, shares insights into its chemistry.

The molecule, as indicated by its name and CAS number, features two phthalic acid groups linked by a hexafluoroisopropylidene bridge. This structure results in a molecular formula of C19H10F6O8 and a molecular weight of approximately 480.27 g/mol. Its physical form is typically a white to off-white powder, with a notable melting point often cited between 240-241°C. The presence of six fluorine atoms in the isopropylidene bridge significantly influences its chemical behavior, increasing electronegativity and thermal stability.

The acidity of the compound, as reflected in its pKa value (often predicted around 2.51), is attributed to the two carboxylic acid groups on each benzene ring. These functional groups are the primary sites for chemical reactions, making the compound an excellent candidate for esterification, amidation, and polymerization reactions. The electronic effects of the fluorinated group also play a role, influencing the reactivity of the aromatic rings and the acidity of the carboxyl groups.

The synthesis of 4,4'-(Hexafluoroisopropylidene)diphthalic Acid typically involves reactions that introduce the hexafluoroisopropylidene moiety onto phthalic acid derivatives or related precursors. While specific industrial synthesis routes can be proprietary, common approaches might involve condensation reactions utilizing hexafluoroacetone or related fluorinated compounds. The process requires careful control of reaction conditions to ensure high yield and purity, which is a cornerstone of our manufacturing process at NINGBO INNO PHARMCHEM CO., LTD.

For entities looking to buy this chemical, understanding these properties is essential for selecting appropriate reaction conditions and downstream applications. Whether it's for creating high-performance polymers, electronic materials, or other specialized organic molecules, a reliable supplier like NINGBO INNO PHARMCHEM CO., LTD. ensures access to a consistent and high-quality product. We are committed to supporting scientific and industrial advancement through our chemical offerings.