10-Bromodecanol, identified by its CAS number 53463-68-6, is a chemical compound that holds significant importance as an intermediate in various sectors of organic chemistry and industry. Characterized as a clear yellow liquid, its molecular structure features a ten-carbon chain terminated by a hydroxyl group at one end and a bromine atom at the other. This bifunctional nature is key to its versatility in chemical synthesis.

The primary method for synthesizing 10-Bromodecanol involves the selective monobromination of 1,10-decanediol. This process requires careful control over reaction conditions, such as the concentration of hydrobromic acid and temperature, to maximize the yield of the desired monobrominated product while minimizing the formation of the dibrominated byproduct, 1,10-dibromodecane. Research has demonstrated that utilizing phase transfer catalysts can significantly improve the efficiency and selectivity of this reaction. Microwave-assisted synthesis also offers a faster alternative to conventional heating methods, reducing reaction times dramatically.

The reactivity of 10-Bromodecanol is dictated by its two primary functional groups. The terminal hydroxyl group behaves like a typical primary alcohol, readily undergoing reactions such as oxidation to form aldehydes or carboxylic acids, esterification, and ether formation. The bromine atom, being a good leaving group, makes the terminal carbon susceptible to nucleophilic substitution reactions. This allows for the introduction of a wide array of other functional groups, such as amines, azides, or halides, enabling the synthesis of diverse chemical derivatives.

The applications of 10-Bromodecanol are extensive, spanning several key industries. In organic synthesis, it serves as a fundamental building block for creating complex molecules. It is extensively used in the pharmaceutical industry for the development of active pharmaceutical ingredients (APIs) and in the agrochemical sector for the production of pesticides and herbicides. Its role in the dye industry and in the synthesis of specialized compounds like insect pheromones further underscores its versatility. Additionally, it finds application in advanced fields such as the synthesis of rotaxane dendrimers and molecules that promote neurite outgrowth, highlighting its importance in cutting-edge research.

NINGBO INNO PHARMCHEM CO.,LTD. plays a crucial role in supplying high-quality 10-Bromodecanol, supporting researchers and manufacturers worldwide. Understanding the synthesis pathways and chemical reactivity of this compound is essential for unlocking its full potential in developing innovative products and solutions across various scientific and industrial disciplines.