Exploring the Chemical Properties and Applications of 3-Bromo-5-fluorobenzotrifluoride
Understanding the fundamental chemical properties of an intermediate is crucial for its effective utilization in synthesis. NINGBO INNO PHARMCHEM CO.,LTD. provides key insights into 3-Bromo-5-fluorobenzotrifluoride (CAS: 130723-13-6), a compound valued for its specific reactivity and applicability in diverse chemical processes.
3-Bromo-5-fluorobenzotrifluoride is characterized by its molecular formula C7H3BrF4 and a molecular weight of approximately 243.00 g/mol. Physically, it typically presents as a colorless to light yellow liquid or a low-melting solid, with a boiling point often cited around 138-139 °C and a density of approximately 1.511 g/mL at 25 °C. These physical attributes are important for handling, storage, and reaction condition optimization.
Chemically, the compound's significance lies in its trifunctional nature. The bromine atom is a versatile handle for various reactions, most notably palladium-catalyzed cross-coupling reactions. This allows for the facile introduction of aryl, vinyl, or alkyl groups, enabling the construction of complex carbon skeletons. The fluorine atom and the highly electron-withdrawing trifluoromethyl group on the benzene ring influence the electronic distribution, affecting the reactivity of the ring and the C-Br bond. This electronic modulation is often exploited in medicinal chemistry to fine-tune the properties of target molecules, such as enhancing lipophilicity, improving metabolic stability, or increasing binding affinity to biological targets.
The applications for 3-Bromo-5-fluorobenzotrifluoride are broad, ranging from the synthesis of pharmaceutical intermediates to its use in the development of specialty chemicals. As a key building block in chemical intermediate synthesis, it is employed in creating molecules that require precise aromatic substitution patterns. Researchers looking to buy 3-Bromo-5-fluorobenzotrifluoride often do so for its specific role in multi-step synthetic pathways designed to yield high-value compounds.
NINGBO INNO PHARMCHEM CO.,LTD. ensures that this compound is available at high purity levels (e.g., 97%), which is critical for reproducible and efficient synthesis. When considering the price and sourcing, opting for a reliable supplier like NINGBO INNO PHARMCHEM CO.,LTD. guarantees access to a material that meets stringent quality standards. This is essential for researchers and manufacturers who depend on the consistency and performance of their chemical inputs.
In conclusion, 3-Bromo-5-fluorobenzotrifluoride is a highly functionalized intermediate whose chemical properties make it an indispensable tool in modern organic synthesis. Its versatility in forming new carbon-carbon bonds and its ability to introduce desirable fluorine-containing motifs make it a valuable asset for pharmaceutical development and the creation of advanced materials. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying this critical compound to meet the evolving needs of the chemical industry.
Perspectives & Insights
Data Seeker X
“This electronic modulation is often exploited in medicinal chemistry to fine-tune the properties of target molecules, such as enhancing lipophilicity, improving metabolic stability, or increasing binding affinity to biological targets.”
Chem Reader AI
“The applications for 3-Bromo-5-fluorobenzotrifluoride are broad, ranging from the synthesis of pharmaceutical intermediates to its use in the development of specialty chemicals.”
Agile Vision 2025
“As a key building block in chemical intermediate synthesis, it is employed in creating molecules that require precise aromatic substitution patterns.”