NINGBO INNO PHARMCHEM CO.,LTD. is a prominent supplier of specialized chemical intermediates, and 1,4-Dibromonaphthalene (CAS 83-53-4) is one of its key offerings. This article explores the synthesis, physicochemical properties, and broad industrial applications of this vital compound, highlighting its significance in advanced materials and chemical processes.

Synthesis of 1,4-Dibromonaphthalene

The synthesis of 1,4-Dibromonaphthalene is typically achieved through the bromination of 1-bromonaphthalene. This process involves reacting 1-bromonaphthalene with bromine in a suitable solvent, such as dichloromethane, often at low temperatures to control the reaction and maximize yield. The result is a compound with bromine atoms precisely located at the 1 and 4 positions of the naphthalene ring, which is crucial for its subsequent reactivity and applications. The efficient and high-yield synthesis pathways contribute to its accessibility for industrial use.

Physicochemical Properties and Purity Standards

1,4-Dibromonaphthalene (C10H6Br2) presents itself as a light orange-beige fine crystalline powder. Its key properties include a melting point of 80-82°C and a density of approximately 1.8 g/cm³. These physical characteristics are indicative of its stable nature. High purity is a critical aspect for its applications, especially in sensitive fields like OLED manufacturing and pharmaceutical synthesis. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. typically ensure purity levels exceeding 98%, verified through analytical techniques such as HPLC and GC, meeting the stringent demands of various industries.

Diverse Industrial Applications

The versatility of 1,4-Dibromonaphthalene is evident in its wide range of applications:

  • OLED Technology: It serves as a critical intermediate in the synthesis of materials for Organic Light-Emitting Diodes (OLEDs). Its structure allows for the creation of compounds with desired electronic and optical properties, contributing to the development of high-performance displays and lighting solutions. As a triplet excitation acceptor, it plays a role in phosphorescent emission, enhancing device efficiency.
  • Pharmaceutical Synthesis: In the pharmaceutical industry, 1,4-Dibromonaphthalene is a valuable building block for creating complex organic molecules. Its reactivity in cross-coupling reactions facilitates the synthesis of potential drug candidates with various biological activities, including enzyme-inhibitory, antifungal, antibacterial, and anticancer properties. This makes it a cornerstone in drug discovery pipelines.
  • Coordination Chemistry: The compound is also utilized in coordination chemistry for the preparation of metal complexes and functional materials. Its bidentate nature and the presence of bromine atoms allow for diverse coordination behaviors.
  • Organic Electronic Devices: Beyond OLEDs, it finds application in other organic electronic devices, such as organic field-effect transistors (OFETs) and organic photovoltaics (OPVs), where its electronic properties are highly beneficial.

Quality Assurance and Supply Chain Reliability

NINGBO INNO PHARMCHEM CO.,LTD. emphasizes quality assurance and supply chain reliability for 1,4-Dibromonaphthalene. By adhering to rigorous production and quality control standards, the company ensures that its products consistently meet the high expectations of its global clientele. For industries requiring this critical intermediate, partnering with a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to high-quality material vital for innovation and production.