Marfey's Reagent (FDAA): Your Solution for Reliable Chiral Compound Analysis
In the complex landscape of chemical and biological analysis, the precise identification and quantification of chiral compounds are often critical for determining functionality, safety, and efficacy. Chirality, the property of molecular asymmetry, leads to the existence of enantiomers, molecules that are mirror images of each other and can exhibit significantly different properties. To address this, advanced analytical techniques are employed, with High-Performance Liquid Chromatography (HPLC) being a cornerstone, often enhanced by specialized reagents like 1-Fluoro-2,4-dinitrophenyl-5-L-alanine Amide (FDAA), also known as Marfey's Reagent, supplied by NINGBO INNO PHARMCHEM CO.,LTD.
Marfey's Reagent is specifically formulated for derivatizing molecules containing amine groups, making it exceptionally useful for amino acid analysis and the broader field of chiral compound analysis. The process involves precolumn derivatization, where FDAA reacts with the target analytes. This reaction forms diastereomeric derivatives, which are crucial because they possess different physical and chemical characteristics. These differences allow for their successful separation using standard reverse-phase HPLC columns, thereby enabling the accurate quantification of enantiomeric pairs. This is particularly important for enantiomeric purity testing, a critical step in pharmaceutical quality control.
NINGBO INNO PHARMCHEM CO.,LTD. provides FDAA with a guaranteed high purity, typically 99%, ensuring that researchers and manufacturers can rely on consistent and accurate results. The price of FDAA reflects its critical role in sensitive analytical applications where precision is non-negotiable. For laboratories focused on developing enantiomerically pure drugs or analyzing complex biological samples, the investment in high-quality FDAA from a reputable source is essential for reliable outcomes.
The utility of FDAA extends across various scientific domains. In biochemical research, it is indispensable for studying protein composition and metabolic pathways through accurate amino acid analysis. The ability to perform precise chiral analysis by HPLC with FDAA also supports the characterization of peptides, the identification of unnatural amino acids, and the assessment of racemization in synthetic processes. Its versatility makes it a go-to reagent for many analytical challenges.
Moreover, understanding the application and procurement of such specialized chemicals is vital for laboratory efficiency. NINGBO INNO PHARMCHEM CO.,LTD. ensures a stable supply of FDAA, allowing research and development pipelines to proceed without interruption. The ability to reliably purchase this reagent empowers scientists to conduct thorough enantiomeric purity testing and other critical analytical procedures with confidence.
In conclusion, 1-Fluoro-2,4-dinitrophenyl-5-L-alanine Amide (FDAA), or Marfey's Reagent, stands as a critical tool for achieving reliable chiral compound analysis via HPLC. Its effectiveness in precolumn derivatization for enantiomeric separation and quantification makes it invaluable for amino acid analysis and beyond. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this essential chemical, facilitating advancements in analytical science and its diverse applications.
Perspectives & Insights
Data Seeker X
“Chirality, the property of molecular asymmetry, leads to the existence of enantiomers, molecules that are mirror images of each other and can exhibit significantly different properties.”
Chem Reader AI
“To address this, advanced analytical techniques are employed, with High-Performance Liquid Chromatography (HPLC) being a cornerstone, often enhanced by specialized reagents like 1-Fluoro-2,4-dinitrophenyl-5-L-alanine Amide (FDAA), also known as Marfey's Reagent, supplied by NINGBO INNO PHARMCHEM CO.”
Agile Vision 2025
“Marfey's Reagent is specifically formulated for derivatizing molecules containing amine groups, making it exceptionally useful for amino acid analysis and the broader field of chiral compound analysis.”