The journey of creating complex organic molecules often begins with meticulously chosen building blocks. 2-Bromo-4-Chlorobenzaldehyde (CAS: 84459-33-6) is one such cornerstone intermediate, indispensable for its role in diverse chemical synthesis pathways. This article provides a comprehensive overview of its synthesis, chemical properties, and applications, highlighting why it is a preferred choice for professionals in organic synthesis and pharmaceutical development.

Understanding the synthesis of 2-Bromo-4-Chlorobenzaldehyde is crucial for its effective utilization. Various routes exist, often starting from substituted benzaldehydes or benzyl alcohols, employing halogenation and oxidation reactions. Manufacturers strive for efficient and scalable methods to produce this compound with high assay purity (≥98.0%) and low moisture content (≤1.0%). The reliability of these synthetic processes ensures that the intermediate meets the stringent quality demands of industries focused on precision chemistry. For those seeking to buy 2-Bromo-4-Chlorobenzaldehyde, understanding these production nuances can guide selection towards the most dependable sources.

The chemical and physical properties of 2-Bromo-4-Chlorobenzaldehyde are key to its versatility. It typically appears as a white to light yellow solid, possessing a molecular formula of C7H4BrClO and a molecular weight of approximately 219.46. Its density is around 1.698 g/cm³, with a boiling point of 264.6°C, indicating reasonable thermal stability for many synthetic operations. These characteristics, combined with its specific functional groups, make it a robust chemical synthesis precursor. The dual halogen substitution offers distinct reactivity, enabling selective transformations that are vital in multi-step syntheses.

The applications of 2-Bromo-4-Chlorobenzaldehyde are extensive, particularly as a pharmaceutical intermediate. It is frequently employed in the synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules, where its structure contributes to the therapeutic efficacy and pharmacokinetic profiles of the final products. The ability to introduce specific functional groups via reactions involving this compound is invaluable in drug discovery and medicinal chemistry. Similarly, in the agrochemical sector, it serves as an essential precursor for developing advanced crop protection agents.

Navigating the landscape of chemical suppliers is important when sourcing this compound. Many manufacturers in China specialize in producing high-quality organic synthesis intermediates like 2-Bromo-4-Chlorobenzaldehyde. By focusing on suppliers that guarantee purity and consistency, researchers and production managers can ensure the success of their projects. The uses of 2-Bromo-4-Chlorobenzaldehyde continue to expand as new synthetic methodologies are developed, solidifying its position as a critical component in the ongoing advancement of chemical sciences and related industries.