2-Amino-5-Iodobenzonitrile (CAS 132131-24-9) is more than just a chemical compound; it's a critical enabler for innovation in the pharmaceutical and fine chemical sectors. Its structure, a benzonitrile ring substituted with an amino group at the 2-position and an iodine atom at the 5-position, offers unique reactivity, making it a sought-after intermediate for complex molecular constructions. This article delves into its properties and applications, providing insights for researchers and manufacturers.

The compound's utility as a pharmaceutical intermediate is well-established. It plays a crucial role in the synthesis of various pharmacologically active molecules. For instance, its use in creating the intermediate for lapatinib, a tyrosine kinase inhibitor, demonstrates its value in oncology drug development. The presence of the iodine atom provides a handle for cross-coupling reactions, such as Suzuki or Heck couplings, which are fundamental in building carbon-carbon bonds essential for complex drug architectures. This makes sourcing reliable specialty aromatic nitriles like 2-Amino-5-iodobenzonitrile crucial for efficient R&D pipelines.

In the realm of organic synthesis reagents, 2-Amino-5-iodobenzonitrile offers significant advantages. Its predictable reactivity allows chemists to design sophisticated synthetic routes. The amino group can be further functionalized, while the nitrile group can be transformed into other functional groups, such as carboxylic acids or amines, expanding its synthetic utility. Companies seeking to perform custom chemical synthesis often specify this compound due to its well-understood behavior in various reaction conditions.

The synthesis of 2-Amino-5-Iodobenzonitrile typically involves the iodination of 2-aminobenzonitrile. Methods often employ iodinating agents in acidic media, with careful control over reaction temperature and time to ensure high yield and purity. Access to manufacturers with robust production capabilities, such as those in China, is vital for obtaining this compound consistently. The ability to buy 2-Amino-5-iodobenzonitrile with guaranteed quality and specifications supports its widespread use in both laboratory research and industrial production. Understanding its role as a 5-iodoanthranilonitrile supplier network component is key to effective procurement strategies.

In summary, 2-Amino-5-Iodobenzonitrile is a cornerstone chemical intermediate. Its critical function in pharmaceutical synthesis, particularly for oncology drugs, and its broad applicability in fine chemical manufacturing make it an indispensable component for scientific advancement. By understanding its chemical properties and ensuring a reliable supply, industries can effectively leverage this versatile molecule for future innovations.