NINGBO INNO PHARMCHEM CO.,LTD. is pleased to present Methanesulfonyl Chloride (MSC), a fundamental reagent that empowers chemists across various disciplines of organic synthesis. Known also as mesyl chloride, this simple yet potent organosulfur compound (CH3SO2Cl) is indispensable for its reactivity and broad range of applications in creating complex organic molecules.

The primary function of MSC in organic synthesis lies in its ability to act as a methanesulfonylating agent. The methanesulfonyl chloride synthesis of methanesulfonates from alcohols is a cornerstone reaction. These methanesulfonate esters are highly valuable intermediates, often employed to introduce the methanesulfonyl group which serves as an excellent leaving group. This property makes them ideal for subsequent substitution, elimination, and reduction reactions, allowing chemists to manipulate molecular structures with precision.

Moreover, the reaction of MSC with amines yields methanesulfonamides. These compounds are known for their stability and are frequently incorporated into molecules to modulate their properties, such as acidity or biological activity. The uses of mesyl chloride in forming these sulfonamides are critical in medicinal chemistry and materials science. The efficiency of these reactions contributes significantly to the overall methanesulfonyl chloride price, making it an economically viable choice for large-scale synthesis projects.

The utility of MSC extends to its role as a precursor for sulfene (CH2=SO2), a highly reactive intermediate that can participate in cycloaddition reactions to form various heterocycles, which are prevalent in many natural products and pharmaceuticals. This ability to generate reactive intermediates further enhances its versatility in organic synthesis.

When considering methanesulfonyl chloride applications, its use as a protecting group for alcohols and amines is also noteworthy. The methanesulfonyl group can be selectively introduced and removed, protecting sensitive functional groups during multi-step synthesis. This strategic protection ensures that reactions occur at desired locations within a molecule, preventing unwanted side reactions and improving the overall yield and purity of the final product.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality Methanesulfonyl Chloride to the scientific community. As a trusted methanesulfonyl chloride supplier, we ensure that our product meets the stringent requirements of organic chemists. The consistent quality and reliable availability of MSC are key factors that drive its widespread adoption in research and industrial applications, making it a truly versatile tool for advancing the field of organic synthesis.