Methyl Methanesulfonate (CAS 1115-84-0): A Deep Dive into its Use as a DNA Alkylating Agent
NINGBO INNO PHARMCHEM CO.,LTD. is a leading provider of fine chemicals, including essential reagents like Methyl Methanesulfonate (CAS 1115-84-0). This compound plays a crucial role in scientific research, particularly in studies involving DNA damage and modification. As a potent DNA alkylating agent, Methyl Methanesulfonate is instrumental in understanding the intricate ways DNA can be altered and how cells respond to such damage. This article explores the significance of MMS in this context and why researchers rely on its availability.
Methyl Methanesulfonate, with its molecular formula C6H14ClNO2S, is characterized by its ability to covalently attach alkyl groups to DNA bases. This process, known as alkylation, can disrupt normal DNA replication and transcription, often leading to mutations. The specific targets for MMS alkylation include guanine and adenine bases, forming adducts like 7-methylguanine. This targeted damage makes it an excellent tool for researchers aiming to study DNA repair mechanisms, such as base excision repair, or to induce specific genetic changes for experimental purposes. If you need to buy methyl methanesulfonate, NINGBO INNO PHARMCHEM CO.,LTD. ensures a product that meets the stringent requirements of scientific research.
The methyl methanesulfonate properties, including its presentation as a powder and its defined melting point, are important for its practical application in laboratories. The reliability of the methyl methanesulfonate appearance as a consistent powder form allows for accurate weighing and preparation of solutions, which is critical for dose-response studies. The broad methyl methanesulfonate application as a model genotoxic agent makes it a staple in many research settings, from academic laboratories studying fundamental biology to pharmaceutical companies evaluating the safety and efficacy of new drugs.
Understanding the methyl methanesulfonate CAS 1115-84-0 designation is crucial for identifying the correct compound and ensuring quality. Researchers often use MMS to investigate the genetic effects of chemical exposures, to screen for compounds that can mitigate DNA damage, or to understand the pathways involved in maintaining genomic stability. The consistent quality provided by suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is paramount for the validity of these experiments. The known effects of methyl methanesulfonate provide a benchmark for evaluating other potentially genotoxic substances.
In conclusion, Methyl Methanesulfonate (CAS 1115-84-0) is a vital fine chemical that serves as a powerful DNA alkylating agent. Its applications in mutagenesis and DNA damage research are extensive, contributing significantly to our understanding of cellular processes and disease mechanisms. NINGBO INNO PHARMCHEM CO.,LTD. is proud to support the scientific community by supplying this essential compound, fostering innovation and discovery in the field.
Perspectives & Insights
Silicon Analyst 88
“The methyl methanesulfonate properties, including its presentation as a powder and its defined melting point, are important for its practical application in laboratories.”
Quantum Seeker Pro
“The reliability of the methyl methanesulfonate appearance as a consistent powder form allows for accurate weighing and preparation of solutions, which is critical for dose-response studies.”
Bio Reader 7
“The broad methyl methanesulfonate application as a model genotoxic agent makes it a staple in many research settings, from academic laboratories studying fundamental biology to pharmaceutical companies evaluating the safety and efficacy of new drugs.”