NINGBO INNO PHARMCHEM CO.,LTD. is committed to empowering chemical professionals with knowledge about critical synthesis intermediates. This guide focuses on 1-Fluoro-3-chloropropane (CAS 462-38-4), a compound whose strategic importance in organic synthesis cannot be overstated, particularly for those involved in pharmaceuticals and specialty chemical development.

Understanding the Core of 1-Fluoro-3-chloropropane

1-Fluoro-3-chloropropane is a halogenated hydrocarbon with the molecular formula C3H6ClF and a molecular weight of 96.53 g/mol. Physically, it is a colorless, transparent liquid. Its key chemical and physical properties, such as a density of approximately 1.0581 g/cm³, a boiling point of 69.68°C, and a refractive index of 1.3871, provide essential data for chemists planning reactions and processes. The presence of both fluorine and chlorine atoms on the propane chain grants it unique reactivity, making it a versatile intermediate. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensure high purity levels (≥99.0%), which is vital for precise chemical synthesis.

Key Applications in Organic Synthesis

The primary utility of 1-fluoro-3-chloropropane lies in its function as an intermediate in organic synthesis. It is extensively used in the pharmaceutical industry as a building block for creating complex molecules, including Active Pharmaceutical Ingredients (APIs). The incorporation of fluorine can improve a drug's metabolic stability, lipophilicity, and overall efficacy. In the agrochemical sector, it contributes to the development of novel pesticides and herbicides. Its application also extends to the synthesis of specialty chemicals, where its unique structure is leveraged to create materials with enhanced properties for sectors like electronics and advanced polymers. Reliable access to this compound is crucial for driving innovation in these fields.

Procurement and Safe Handling Recommendations

For professionals seeking to procure 1-fluoro-3-chloropropane, partnering with reputable manufacturers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., offers a reliable supply chain with competitive pricing and high-quality products. It is imperative to follow recommended handling and storage procedures. The compound should be stored in a cool, well-ventilated area, away from heat, sparks, and open flames. Appropriate personal protective equipment (PPE) should always be used when handling this chemical. Understanding the specific 1-fluoro-3-chloropropane properties and consulting the Safety Data Sheet (SDS) are fundamental steps for ensuring workplace safety and product integrity.

Conclusion

1-Fluoro-3-chloropropane is a cornerstone intermediate that empowers chemists to create cutting-edge products. Its dual halogen functionality and presence in key industries underscore its importance. By focusing on quality sourcing and safe practices, chemical professionals can effectively harness the synthetic potential of this essential compound.