NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing comprehensive information about the chemicals we supply, ensuring safe and effective use. 3-Bromonitrobenzene (CAS 585-79-5) is a valuable chemical intermediate, and understanding its properties and proper handling procedures is paramount for all users.

Physical Properties:
3-Bromonitrobenzene typically appears as a light yellow crystalline solid. It has a melting point in the range of 51-54°C and a boiling point around 256°C. While it exhibits moderate solubility in common organic solvents like ethanol, benzene, and ether, it is largely insoluble in water. These physical characteristics are important to consider during storage, processing, and waste management.

Chemical Reactivity:
As an aromatic compound with both a bromine atom and a nitro group, 3-Bromonitrobenzene is chemically reactive. The electron-withdrawing nitro group deactivates the benzene ring towards electrophilic aromatic substitution, directing incoming electrophiles to the meta position. Conversely, the bromine atom can be a site for nucleophilic substitution or participate in metal-catalyzed cross-coupling reactions. This dual reactivity makes it a versatile intermediate.

Safety and Handling Precautions:
3-Bromonitrobenzene is classified as a hazardous substance and requires careful handling. It can be harmful if inhaled, swallowed, or absorbed through the skin. It is also an irritant to the eyes, respiratory system, and skin. Therefore, appropriate personal protective equipment (PPE) is essential:

  • Respiratory Protection: Use in a well-ventilated area or with appropriate respiratory protection if dust or vapors are generated.
  • Hand Protection: Wear chemical-resistant gloves (e.g., nitrile, neoprene).
  • Eye Protection: Use safety goggles or a face shield.
  • Skin Protection: Wear protective clothing, including lab coats and closed-toe shoes.

In case of contact, immediately rinse affected areas with plenty of water and seek medical advice. Avoid breathing dust or vapors. Keep containers tightly closed in a dry, cool, and well-ventilated place, away from sources of ignition and incompatible materials such as strong oxidizing agents and strong acids.

Storage and Disposal:
Store 3-Bromonitrobenzene in its original, tightly sealed container. Keep it away from heat, sparks, and open flames. Proper ventilation in the storage area is crucial. Disposal of waste material should be conducted in accordance with local, regional, and national environmental regulations. It is advisable to consult with environmental safety professionals for guidance on disposal methods.

At NINGBO INNO PHARMCHEM CO.,LTD., we prioritize safety and product stewardship. We encourage all our customers to review the Safety Data Sheet (SDS) for 3-Bromonitrobenzene prior to handling and use. Our team is also available to answer any specific questions regarding the safe storage, handling, and application of this chemical intermediate.