Cyclobutyl Bromide (CAS: 4399-47-7) is a valuable chemical compound known for its utility in organic synthesis. As a leading supplier, NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive information on its properties and best practices for handling and storage to ensure safe and effective use.

Physically, Cyclobutyl Bromide is characterized as a colorless liquid. Its key chemical and physical properties include a density of approximately 1.434 g/cm³, a boiling point around 108°C, and a flash point of 72°F. The refractive index is reported as 1.479. These characteristics are vital for chemists when planning reactions and understanding the compound's behavior under various conditions. The high assay, typically ≥98.0%, ensures its suitability for precise chemical transformations.

When considering the cyclobutyl bromide properties for specific applications, its role as an alkyl halide is prominent. The bromine atom acts as a good leaving group, facilitating nucleophilic substitution reactions. This reactivity makes it a versatile building block for creating carbon-carbon bonds and introducing the cyclobutyl moiety into target molecules. Its application extends to laboratory research and development, as well as serving as a crucial component in the synthesis of pharmaceutical intermediates.

Safe handling and storage are paramount when working with Cyclobutyl Bromide. It is classified as a flammable liquid and can cause skin and eye irritation, and may cause respiratory irritation. Therefore, it should always be handled in a well-ventilated area, preferably under a fume hood, and appropriate personal protective equipment (PPE) such as gloves, safety glasses, and lab coats should be worn. Avoid contact with skin, eyes, and clothing, and avoid breathing vapors or mist. Precautions should be taken to prevent static discharge.

For storage, Cyclobutyl Bromide should be kept in a cool, well-ventilated place, away from heat, sparks, and open flames. Containers must be kept tightly closed. Recommended storage temperatures often specify a cool environment, such as 0-6°C, to maintain its stability and quality over time. Adhering to these storage guidelines ensures the integrity of the product for its intended cyclobutyl bromide uses.

NINGBO INNO PHARMCHEM CO.,LTD. emphasizes the importance of consulting the Safety Data Sheet (SDS) for detailed information on hazards, first aid measures, fire-fighting measures, and accidental release measures. By understanding and implementing these guidelines, users can safely and effectively utilize Cyclobutyl Bromide in their synthetic endeavors, whether for research or production purposes.