For successful chemical synthesis, a thorough understanding of the properties of the starting materials and intermediates is indispensable. Fmoc-(S)-3-Amino-4-(4-bromo-phenyl)-butyric acid, a key building block in advanced organic synthesis, possesses a unique set of physical and chemical characteristics that dictate its utility and handling. NINGBO INNO PHARMCHEM CO.,LTD. provides detailed information on this compound to aid researchers in their planning and execution of synthesis projects.

Physically, Fmoc-(S)-3-Amino-4-(4-bromo-phenyl)-butyric acid is typically presented as a white to off-white solid or powder. This solid form, with a melting point often cited in the range of 177-178 °C, indicates a stable crystalline structure at room temperature. Its molecular formula, C25H22BrNO4, and molecular weight of approximately 480.35 g/mol are fundamental data points for stoichiometric calculations in reactions. When you are ready to buy Fmoc-(S)-3-Amino-4-(4-bromo-phenyl)-butyric acid, these specifications help in planning material quantities accurately.

Chemically, the compound's structure is rich in functional groups that lend themselves to diverse synthetic transformations. The N-terminal Fmoc group is a labile protecting group for the amine, readily removable under mild basic conditions (e.g., using piperidine). This selective deprotection is the cornerstone of Fmoc-based peptide synthesis. The carboxylic acid group provides a site for esterification or amide bond formation, crucial for peptide coupling and other derivatizations. The central chiral center bearing the protected amine and the substituted alkyl chain is critical for stereoselective synthesis.

The most distinctive chemical feature is the para-brominated phenyl ring. This aryl bromide moiety is highly amenable to palladium-catalyzed cross-coupling reactions, such as Suzuki, Sonogashira, and Heck couplings. These reactions allow for the introduction of carbon-carbon bonds, enabling the synthesis of more complex aromatic systems or the attachment of diverse functional groups. This versatility makes it an invaluable amino acid building block for creating novel organic molecules, peptidomimetics, and potential drug candidates.

For researchers sourcing Fmoc amino acid derivatives, understanding solubility is also important. While typically soluble in polar organic solvents like DMF or DMSO, its exact solubility can vary, and preparation of solutions often requires careful consideration of the solvent system and temperature. NINGBO INNO PHARMCHEM CO.,LTD. ensures that the purity of our Fmoc-(S)-3-Amino-4-(4-bromo-phenyl)-butyric acid is consistently high, minimizing interference from impurities in critical reactions.

In essence, the properties of Fmoc-(S)-3-Amino-4-(4-bromo-phenyl)-butyric acid—its solid form, well-defined melting point, labile Fmoc protection, reactive carboxylic acid, chiral center, and versatile aryl bromide—collectively make it an indispensable tool for chemists engaged in complex synthesis projects. Partnering with a reliable Fmoc-(S)-3-Amino-4-(4-bromo-phenyl)-butyric acid supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures you have access to this powerful synthetic intermediate.