Understanding the fundamental properties and synthesis of key chemical compounds is essential for driving innovation in chemistry. L-Glutamic acid gamma-benzyl ester, known as H-Glu(OBzl)-OH (CAS 1676-73-9), is a compound that warrants detailed scientific exploration due to its significant utility. Ningbo Inno Pharmchem Co., Ltd., a specialist in amino acid derivatives, aims to elucidate the scientific underpinnings of this important molecule.

Chemically, H-Glu(OBzl)-OH is a derivative of glutamic acid where the gamma-carboxyl group is protected by a benzyl ester. This protection strategy is a common and effective method in organic synthesis, particularly for managing the reactivity of carboxylic acids during complex multi-step processes. The compound typically presents as a white crystalline powder, with a well-defined melting point ranging from 181-182°C. Its molecular formula is C12H15NO4, and it has a molecular weight of approximately 237.25 g/mol. These parameters are crucial for stoichiometric calculations and reaction planning. The scientific rationale for using H-Glu(OBzl)-OH often lies in its role as a protected amino acid building block, making it easier for researchers to buy H-Glu(OBzl)-OH for their synthetic needs.

The synthesis of H-Glu(OBzl)-OH typically involves the esterification of L-glutamic acid with benzyl alcohol, often under acidic catalysis, with careful control to ensure regioselectivity at the gamma-carboxyl group. Alternatively, it can be prepared from the corresponding anhydride or via coupling reactions. The resulting product is then purified to achieve the high purity required for its downstream applications. Its primary use is in peptide synthesis, where it is incorporated into growing peptide chains using standard coupling reagents. The benzyl protecting group can be readily removed, often through hydrogenolysis, to reveal the free carboxylic acid when needed.

Beyond peptide synthesis, H-Glu(OBzl)-OH serves as a valuable intermediate in the synthesis of various organic compounds, including pharmaceuticals and specialty chemicals. Its chiral center makes it a useful starting material for stereoselective synthesis. As a manufacturer in China, Ningbo Inno Pharmchem Co., Ltd. ensures that the production of CAS 1676-73-9 adheres to strict scientific protocols, guaranteeing quality and consistency. Researchers can depend on us for reliable sourcing, competitive pricing, and detailed technical information for this essential amino acid derivative.

In conclusion, a thorough understanding of the scientific properties and synthesis of H-Glu(OBzl)-OH is key to leveraging its full potential. Ningbo Inno Pharmchem Co., Ltd. is committed to providing high-quality H-Glu(OBzl)-OH to support scientific research and development, offering a reliable source for this fundamental chemical building block.