At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing a deep understanding of the chemicals we supply. Mequinol, chemically known as 4-Methoxyphenol or 4-Hydroxyanisole, is a fascinating organic compound with a distinct set of properties and synthesis pathways. Understanding these scientific underpinnings is crucial for researchers and manufacturers who utilize Mequinol in their diverse applications, from industrial stabilization to dermatological treatments. This exploration delves into the molecular structure, physical characteristics, and common synthesis routes of this valuable chemical.

Mequinol (4-Methoxyphenol) has the molecular formula C7H8O2 and a molar mass of approximately 124.14 g/mol. It typically appears as a white, waxy solid or crystalline powder. Its melting point is around 52.5°C, and it has a boiling point of 243°C. Mequinol exhibits solubility in various organic solvents like ethanol, ether, acetone, and benzene, and has a moderate solubility in water (around 40 g/L at 25°C). Its chemical structure features a phenol ring with a methoxy group attached at the para position, a configuration that dictates its reactivity and utility. The pKa of Mequinol is approximately 10.05, indicating its weak acidic properties.

The synthesis of Mequinol commonly involves the methylation of hydroquinone. One prevalent method utilizes hydroquinone as the starting material, with methylating agents such as dimethyl sulfate or methanol in the presence of a catalyst like sulfuric acid or solid acid resins. Another established route involves the free radical reaction between p-benzoquinone and methanol. Newer methods also explore the reaction of hydroquinone with methanol in the presence of p-benzoquinone under specific conditions. The choice of synthesis method often depends on factors like cost, desired purity, and environmental considerations. The efficient production of high-purity Mequinol is key to its widespread industrial adoption.

The scientific community also notes Mequinol's role as a metabolite and its potential as a biomarker, being naturally present in foods like anise and sweet marjoram. However, its most prominent applications stem from its chemical reactivity. As a polymerization inhibitor, it effectively scavenges free radicals, crucial for stabilizing reactive monomers. In dermatology, its depigmenting effects are attributed to its interaction with tyrosinase, the enzyme responsible for melanin production. The careful control of Mequinol's synthesis and purification ensures its efficacy and safety across its many applications, a commitment that NINGBO INNO PHARMCHEM CO.,LTD. upholds.