NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-quality chemical intermediates, including Diethylcarbamoyl Chloride (CAS 88-10-8). This compound's utility in various industrial processes, particularly in pharmaceuticals and fine chemicals, stems from its specific synthesis routes and reactivity. This article explores the common methods for synthesizing Diethylcarbamoyl Chloride and its fundamental chemical properties.

The synthesis of Diethylcarbamoyl Chloride typically involves the reaction of diethylamine with a chlorinating agent. One common method utilizes phosgene (COCl2) reacting with diethylamine. This reaction forms Diethylcarbamoyl Chloride and hydrogen chloride as a byproduct. Another approach involves using less hazardous reagents like triphosgene, which offers a safer alternative to gaseous phosgene while achieving similar synthetic outcomes. The precise control of reaction conditions, such as temperature and stoichiometry, is crucial for maximizing yield and purity.

The diethylcarbamoyl chloride chemical properties are key to its application. With the molecular formula C5H10ClNO and a molecular weight of approximately 135.59 g/mol, it is often described as a liquid, ranging from clear yellow to brownish, though it can also appear as a white powder depending on its form and purity. Its reactivity with water is a significant characteristic; it readily hydrolyzes to form diethylamine and hydrochloric acid, releasing corrosive and toxic fumes. This reactivity mandates careful handling and storage in moisture-free environments.

Furthermore, Diethylcarbamoyl Chloride acts as an effective acylating agent and a building block in organic synthesis. It is used to introduce the N,N-diethylcarbamoyl group into molecules, a step often required in the preparation of pharmaceuticals and agrochemicals. The potential hazards associated with Diethylcarbamoyl Chloride, including its irritant and potentially mutagenic properties, mean that adherence to strict safety protocols when handling it is non-negotiable. Businesses looking to buy diethylcarbamoyl chloride must ensure their suppliers provide comprehensive safety data.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying Diethylcarbamoyl Chloride that meets rigorous purity standards. By understanding the intricacies of its synthesis and properties, our clients can optimize their processes and ensure the safe and efficient use of this valuable chemical intermediate. For inquiries about diethylcarbamoyl chloride price or bulk orders, please contact our sales team.