Understanding the synthesis and properties of key chemical intermediates is fundamental to unlocking their full potential. NINGBO INNO PHARMCHEM CO.,LTD. provides insights into 2-(Trimethylsilyloxy)ethyl Methacrylate (CAS 17407-09-9), a compound whose synthesis and chemical characteristics are critical for its diverse applications in polymer science and beyond.

The synthesis of 2-(Trimethylsilyloxy)ethyl Methacrylate typically involves the esterification of methacrylic acid with 2-(trimethylsilyloxy)ethanol. This reaction is commonly catalyzed by acids, such as sulfuric acid or p-toluenesulfonic acid (PTSA). While sulfuric acid offers high efficiency, PTSA is often preferred for its milder conditions and reduced by-product formation. Optimization of reaction parameters, including temperature and reaction time, is crucial for achieving high yields and purity. For instance, conducting the reaction at around 80-90°C for several hours with an acid catalyst can yield the desired product with good purity. Industrial production often employs continuous flow reactors to enhance efficiency and consistency, minimizing thermal degradation and improving heat transfer.

A critical aspect of TMSHEMA synthesis and handling is the presence of an inhibitor, such as BHT (Butylated hydroxytoluene) or MEHQ (4-Methoxyphenol), to prevent premature polymerization. These inhibitors are typically added in low concentrations (50-100 ppm) and are essential for maintaining the stability of the monomer during storage and transportation. Proper storage conditions, usually under an inert atmosphere at 2-8°C, are also vital to preserve its integrity.

Chemically, 2-(Trimethylsilyloxy)ethyl Methacrylate is characterized by its methacrylate functionality, which readily participates in free radical polymerization. This allows it to form homopolymers or copolymers with a wide range of other vinyl monomers. The standout feature, however, is the trimethylsilyloxy group. This silyl ether linkage is susceptible to hydrolysis, readily breaking down in the presence of water or acids to yield the corresponding alcohol, in this case, 2-hydroxyethyl methacrylate (HEMA). This hydrolytic lability is a powerful tool for polymer modification techniques, enabling the synthesis of functional polymers that can respond to environmental stimuli or undergo further chemical transformations.

The compound's physical properties include being a colorless to light yellow liquid or powder, with a density around 0.928 g/cm³ at 25°C and a relatively high flash point (around 76.7°C). Its solubility can be limited in polar solvents but is generally good in common organic solvents used in polymerization. These properties inform its handling, processing, and application, particularly when designing solvent-based formulations or reaction systems.

NINGBO INNO PHARMCHEM CO.,LTD. specializes in providing high-quality intermediates like TMSHEMA, ensuring that meticulous attention is paid to synthesis, purification, and stabilization. Our expertise in producing compounds that are vital for specialty methacrylate monomers for advanced polymers and other high-value chemical products allows our clients to achieve their innovative goals with confidence.