The scientific community's exploration of longevity has led to the discovery and validation of several key compounds that influence the aging process. Among the most promising is Alpha-Ketoglutarate (AKG), and its more stable form, Calcium Alpha-Ketoglutarate (Ca-AKG), which is demonstrating significant potential in extending both healthspan and lifespan.

NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of supplying high-quality Ca-AKG, a vital metabolite that serves as a cornerstone for research into aging and rejuvenation. The groundbreaking studies on AKG have provided compelling evidence for its efficacy across various model organisms, solidifying its position in the field of anti-aging science.

Research has consistently shown that AKG supplementation can lead to significant increases in lifespan. In studies involving roundworms and fruit flies, AKG administration resulted in extended life expectancies. More notably, experiments with mice have revealed that AKG can extend lifespan by 12-16% and healthspan by 40-52%. This means not only do the subjects live longer, but they also remain healthier and more disease-free for a greater proportion of their lives. This compression of morbidity is a key goal in longevity research.

The mechanisms behind alpha-ketoglutarate lifespan extension are multifaceted. Ca-AKG plays a critical role in energy metabolism, acting as an intermediate in the Krebs cycle, which generates ATP – the primary energy currency of cells. As AKG levels decline with age, cellular energy production can become less efficient. Supplementing with Ca-AKG helps to restore these vital metabolic functions.

Furthermore, Ca-AKG is implicated in the regulation of epigenetic processes. It acts as a cofactor for enzymes involved in DNA methylation and demethylation, which are crucial for controlling gene expression. By supporting healthy epigenetic patterns, Ca-AKG may help to counteract age-related epigenetic drift, promoting cellular resilience and potentially reversing some aspects of biological aging.

The compound's ability to support mitochondrial function, enhance cellular detoxification, and even promote collagen production for skin health further highlights its comprehensive benefits. These diverse actions contribute to a holistic approach to anti-aging, addressing multiple facets of the aging process simultaneously.

At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing the scientific community and product developers with the highest quality Ca-AKG. Our dedication to purity and consistency ensures that researchers and formulators can rely on our product for groundbreaking studies and innovative applications aimed at improving healthspan and lifespan.

Embrace the future of longevity research with Alpha-Ketoglutarate. Partner with NINGBO INNO PHARMCHEM CO.,LTD. to access premium Ca-AKG and contribute to the scientific endeavor of extending healthy human life.