The Chemical Profile of 4-Fluoroguaiacol (CAS 450-93-1): Properties and Synthesis Insights
Understanding the intricate chemical properties of a compound is fundamental to its effective utilization in research and industry. 4-Fluoroguaiacol, designated by CAS number 450-93-1, is a compound that warrants close examination due to its role as a versatile intermediate. Also referred to as 4-Fluoro-2-methoxyphenol, its chemical structure and physical characteristics dictate its potential applications.
At its core, 4-Fluoroguaiacol possesses the molecular formula C7H7FO2, with a molecular weight of approximately 142.13 g/mol. Physically, it is described as a clear liquid, often exhibiting a pale yellow hue. Key physical constants that are crucial for chemical engineers and researchers include its boiling point, which is reported around 195°C, and its density, approximately 1.247 g/mL at 25°C. These parameters are essential for designing reaction vessels, optimizing separation processes, and ensuring safe handling and storage.
The synthesis of 4-Fluoroguaiacol often involves specific organic reaction pathways. While detailed proprietary synthesis methods may vary, general approaches can involve the selective fluorination of guaiacol derivatives or the modification of suitably substituted phenols. The incorporation of the fluorine atom is a critical step, influencing the compound's electron distribution and reactivity. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. employ established and optimized synthesis routes to ensure consistent yield and high purity of 4-Fluoro-2-methoxyphenol, meeting the rigorous demands of the chemical industry.
The chemical reactivity of 4-Fluoroguaiacol stems from its phenolic hydroxyl group, the methoxy group, and the electronegative fluorine atom. These functional groups allow it to participate in a variety of reactions, including etherification, esterification, and electrophilic aromatic substitution. Its utility as a building block for more complex fluorinated organic molecules makes it an important intermediate in the fine chemical sector. NINGBO INNO PHARMCHEM CO.,LTD. contributes to this field by providing reliable access to high-quality 4-Fluoroguaiacol, facilitating research and industrial production.
For those involved in chemical development, grasping the chemical profile of 4-Fluoroguaiacol is essential. Its properties not only define its handling and reaction behavior but also its potential applications, ranging from the synthesis of specialized materials to its use as an intermediate in the pharmaceutical and agrochemical industries. NINGBO INNO PHARMCHEM CO.,LTD. supports these endeavors by ensuring a consistent supply of this vital chemical intermediate, backed by quality assurance and technical expertise.
Perspectives & Insights
Data Seeker X
“The incorporation of the fluorine atom is a critical step, influencing the compound's electron distribution and reactivity.”
Chem Reader AI
“employ established and optimized synthesis routes to ensure consistent yield and high purity of 4-Fluoro-2-methoxyphenol, meeting the rigorous demands of the chemical industry.”
Agile Vision 2025
“The chemical reactivity of 4-Fluoroguaiacol stems from its phenolic hydroxyl group, the methoxy group, and the electronegative fluorine atom.”