Propionyl Bromide, identified by its CAS number 598-22-1, is an acyl halide that holds significant interest due to its characteristic reactivity and broad utility in organic synthesis. Understanding its chemical structure, synthesis pathways, and reaction mechanisms is fundamental for chemists aiming to effectively utilize this compound.

Chemically, Propionyl Bromide is characterized by the presence of a carbonyl group adjacent to a bromine atom, making the carbon atom highly electrophilic. This electrophilicity drives its participation in a variety of nucleophilic acyl substitution reactions. For instance, it readily reacts with alcohols to form esters, with amines to form amides, and can be used in Friedel-Crafts acylation reactions to introduce the propionyl group onto aromatic rings.

The synthesis of Propionyl Bromide typically involves the reaction of propionic acid or its derivatives with brominating agents. Common methods include the reaction of propionic acid with phosphorus tribromide (PBr3) or thionyl bromide (SOBr2). Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. employ optimized synthesis routes to achieve high yields and purity, often exceeding 99%, which is critical for its applications in fine chemical synthesis.

The reactivity of Propionyl Bromide also necessitates careful handling. As an acid halide, it is sensitive to moisture and can react vigorously with water, producing hydrobromic acid (HBr) and propionic acid. This reaction underscores the importance of storing Propionyl Bromide in tightly sealed containers in a dry environment and using appropriate personal protective equipment when handling it. NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive safety data sheets to guide users on these aspects.

For those looking to buy Propionyl Bromide, understanding its chemical behavior allows for better planning of synthetic strategies and ensures efficient use of this valuable intermediate. The competitive price and reliable supply from manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. make it an accessible reagent for both research and industrial applications.

In conclusion, the chemistry of Propionyl Bromide is defined by its reactivity as an acyl halide. Its synthesis and subsequent reactions are vital processes in the chemical industry, and NINGBO INNO PHARMCHEM CO.,LTD. is a key contributor in providing this essential compound with high purity and reliable availability.